» Authors » Christopher D Roberts

Christopher D Roberts

Explore the profile of Christopher D Roberts including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 21
Citations 257
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
11.
Roberts C, Leaper D, Assadian O
Adv Wound Care (New Rochelle) . 2017 Feb; 6(2):63-71. PMID: 28224049
The topical use of antiseptics for wound care has a role in an antimicrobial stewardship strategy. However, the details of this role need clarification. Further clinical research into the use...
12.
Nherera L, Trueman P, Roberts C, Berg L
Burns . 2017 Feb; 43(5):939-948. PMID: 28161149
Objective: The purpose of this systematic review and meta-analysis was to assess the clinical effectiveness of nanocrystalline silver compared to alternative silver delivery systems (silver sulphadiazine [SSD] and silver nitrate)...
13.
Roberts C, Oeckler R
Respir Care . 2015 Sep; 60(10):1522-5. PMID: 26405189
No abstract available.
14.
Maynard A, Roberts C
J Med Chem . 2015 Aug; 59(9):4189-201. PMID: 26262898
Although lead optimization (LO) is by definition a process, process-centric analysis and visualization of this important phase of pharmaceutical R&D has been lacking. Here we describe a simple statistical framework...
15.
Cunningham S, Roberts C, Frajka-Williams E, Johns W, Hobbs W, Palmer M, et al.
Geophys Res Lett . 2015 Jun; 40(23):6202-6207. PMID: 26074634
[1] Observations show that the upper 2 km of the subtropical North Atlantic Ocean cooled throughout 2010 and remained cold until at least December 2011. We show that these cold...
16.
Kazmierski W, Maynard A, Duan M, Baskaran S, Botyanszki J, Crosby R, et al.
J Med Chem . 2014 Feb; 57(5):2058-73. PMID: 24568313
Rapid clinical progress of hepatitis C virus (HCV) replication inhibitors, including these selecting for resistance in the NS5A region (NS5A inhibitors), promises to revolutionize HCV treatment. Herein, we describe our...
17.
Roberts C
Int Wound J . 2013 Oct; 10(5):617. PMID: 24074374
No abstract available.
18.
Maynard A, Crosby R, Ellis B, Hamatake R, Hong Z, Johns B, et al.
J Med Chem . 2013 May; 57(5):1902-13. PMID: 23672667
A boronic acid moiety was found to be a critical pharmacophore for enhanced in vitro potency against wild-type hepatitis C replicons and known clinical polymorphic and resistant HCV mutant replicons....
19.
Miller J, Chong P, Shotwell J, Catalano J, Tai V, Fang J, et al.
J Med Chem . 2013 Apr; 57(5):2107-20. PMID: 23544424
We describe the preclinical development and in vivo efficacy of a novel chemical series that inhibits hepatitis C virus replication via direct interaction with the viral nonstructural protein 4B (NS4B)....
20.
Tripati A, Roberts C, Eagle R
Science . 2009 Oct; 326(5958):1394-7. PMID: 19815724
The carbon dioxide (CO2) content of the atmosphere has varied cyclically between approximately 180 and approximately 280 parts per million by volume over the past 800,000 years, closely coupled with...