Matthew E Mead
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Explore the profile of Matthew E Mead including associated specialties, affiliations and a list of published articles.
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30
Citations
554
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Recent Articles
1.
Steenwyk J, Knowles S, Bastos R, Balamurugan C, Rinker D, Mead M, et al.
Nat Commun
. 2024 Sep;
15(1):8412.
PMID: 39333551
Cryptic fungal pathogens pose disease management challenges due to their morphological resemblance to known pathogens. Here, we investigated the genomes and phenotypes of 53 globally distributed isolates of Aspergillus section...
2.
Pinzan C, Valero C, de Castro P, Silva J, Earle K, Liu H, et al.
Nat Microbiol
. 2024 Aug;
9(10):2710-2726.
PMID: 39191887
Aspergillus fumigatus causes aspergillosis and relies on asexual spores (conidia) for initiating host infection. There is scarce information about A. fumigatus proteins involved in fungal evasion and host immunity modulation....
3.
Correa Dos Santos R, Mead M, Steenwyk J, Rivero-Menendez O, Alastruey-Izquierdo A, Goldman G, et al.
Front Fungal Biol
. 2023 Sep;
2:723051.
PMID: 37744093
Certain fungi cause aspergillosis, a set of diseases that typically affect immunocompromised individuals. Most cases of aspergillosis are caused by , which infects millions of people annually. Some closely related...
4.
Valero C, Pinzan C, de Castro P, van Rhijn N, Earle K, Liu H, et al.
bioRxiv
. 2023 Sep;
PMID: 37662192
, an important pulmonary fungal pathogen causing several diseases collectively called aspergillosis, relies on asexual spores or conidia for initiating host infection. Here, we used a phylogenomic approach to compare...
5.
Steenwyk J, Knowles S, Bastos R, Balamurugan C, Rinker D, Mead M, et al.
bioRxiv
. 2023 Jul;
PMID: 37461539
Cryptic fungal pathogens pose significant identification and disease management challenges due to their morphological resemblance to known pathogenic species while harboring genetic and (often) infectionrelevant trait differences. The cryptic fungal...
6.
Mead M, de Castro P, Steenwyk J, Gangneux J, Hoenigl M, Prattes J, et al.
Microbiol Spectr
. 2023 Mar;
:e0512822.
PMID: 36946762
Secondary infections caused by the pulmonary fungal pathogen Aspergillus fumigatus are a significant cause of mortality in patients with severe coronavirus disease 19 (COVID-19). Even though epithelial cell damage and...
7.
Brown A, Mead M, Steenwyk J, Goldman G, Rokas A
Front Fungal Biol
. 2023 Mar;
3.
PMID: 36866034
Invasive aspergillosis is a deadly fungal disease; more than 400,000 patients are infected worldwide each year and the mortality rate can be as high as 50-95%. Of the ~450 species...
8.
Horta M, Steenwyk J, Mead M, Dos Santos L, Zhao S, Gibbons J, et al.
mBio
. 2022 Jun;
13(4):e0151922.
PMID: 35766381
Aspergillus fumigatus is both an environmental saprobe and an opportunistic human fungal pathogen. Knowledge of genomic variation across A. fumigatus isolates is essential for understanding the evolution of pathogenicity, virulence,...
9.
Steenwyk J, Buida T, Goncalves C, Goltz D, Morales G, Mead M, et al.
Genetics
. 2022 May;
221(3).
PMID: 35536198
Bioinformatic analysis-such as genome assembly quality assessment, alignment summary statistics, relative synonymous codon usage, file format conversion, and processing and analysis-is integrated into diverse disciplines in the biological sciences. Several...
10.
Steenwyk J, Mead M, de Castro P, Valero C, Damasio A, Dos Santos R, et al.
Microbiol Spectr
. 2021 Jun;
9(1):e0001021.
PMID: 34106569
The ongoing global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for coronavirus disease 2019 (COVID-19), first described in Wuhan, China. A subset of COVID-19...