Christopher D Richards
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Explore the profile of Christopher D Richards including associated specialties, affiliations and a list of published articles.
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12
Citations
183
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Recent Articles
1.
Sampedro Castaneda M, Tonini R, Richards C, Stocker M, Pedarzani P
Neuropharmacology
. 2019 Aug;
158:107738.
PMID: 31447417
Small conductance Ca-activated K (SK) channels are expressed throughout the soma and dendrites of pyramidal neurons in the neocortex and hippocampal formation, where they participate in the local regulation of...
2.
Richards C, Warr C, Burke R
PLoS One
. 2017 Jul;
12(7):e0181237.
PMID: 28704512
Zinc absorption in animals is thought to be regulated in a local, cell autonomous manner with intestinal cells responding to dietary zinc content. The Drosophila zinc transporter Zip88E shows strong...
3.
Richards C, Burke R
Arch Biochem Biophys
. 2016 Jul;
611:142-149.
PMID: 27453039
The core zinc transport machinery is well conserved between invertebrates and mammals, with the vinegar fly Drosophila melanogaster having clear homologues of all major groups of mammalian ZIP and ZNT...
4.
Richards C, Warr C, Burke R
Int J Biochem Cell Biol
. 2015 Nov;
69:11-9.
PMID: 26545796
Dietary zinc is the principal source of zinc in eukaryotes, with its uptake and distribution controlled by a complex network of numerous membrane-spanning transport proteins. Dietary absorption is achieved by...
5.
Richards C, Burke R
Biometals
. 2015 Sep;
28(6):967-74.
PMID: 26411574
While the effects of systemic zinc ion deficiency and toxicity on animal health are well documented, the impacts of localized, tissue-specific disturbances in zinc homeostasis are less well understood. Previously...
6.
Dechen K, Richards C, Lye J, Hwang J, Burke R
Int J Biochem Cell Biol
. 2015 Jan;
60:23-33.
PMID: 25562517
Movement of zinc ions across cellular membranes is achieved mainly by two families of zinc transport genes encoding multi-transmembrane domain proteins. Members of the Zip family generally transport zinc into...
7.
Lye J, Richards C, Dechen K, Warr C, Burke R
J Biol Inorg Chem
. 2013 Jan;
18(3):323-32.
PMID: 23322169
Members of the ZIP (SLC39A) and ZnT (SLC30A) families of transmembrane domain proteins are predicted to transport the essential transition metal zinc across membranes, regulating cellular zinc content and distribution...
8.
Tonini R, Ferraro T, Sampedro-Castaneda M, Cavaccini A, Stocker M, Richards C, et al.
J Neurophysiol
. 2012 Dec;
109(6):1514-24.
PMID: 23255726
In hippocampal pyramidal neurons, voltage-gated Ca(2+) channels open in response to action potentials. This results in elevations in the intracellular concentration of Ca(2+) that are maximal in the proximal apical...
9.
Lye J, Richards C, Dechen K, Paterson D, de Jonge M, Howard D, et al.
J Exp Biol
. 2012 Jun;
215(Pt 18):3254-65.
PMID: 22693027
The heavy metal zinc is an essential component of the human diet and is incorporated as a structural component in up to 10% of all mammalian proteins. The physiological importance...
10.
Griesinger C, Richards C, Ashmore J
Nature
. 2005 Apr;
435(7039):212-5.
PMID: 15829919
Ribbon-type synapses in inner hair cells of the mammalian cochlea encode the complexity of auditory signals by fast and tonic release through fusion of neurotransmitter-containing vesicles. At any instant, only...