Christopher D Rae
Overview
Explore the profile of Christopher D Rae including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
90
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0
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Recent Articles
1.
Huang Y, Alumasa J, Callaghan L, Baugh R, Rae C, Keiler K, et al.
Antimicrob Agents Chemother
. 2019 Mar;
63(4).
PMID: 30917982
is a leading cause of infection in the United States, and due to the rapid development of resistance, new antibiotics are constantly needed. -Translation is a particularly promising antibiotic target...
2.
Rae C, Gordiyenko Y, Ramakrishnan V
Science
. 2019 Feb;
363(6428):740-744.
PMID: 30765567
During trans-translation, transfer-messenger RNA (tmRNA) and small protein B (SmpB) together rescue ribosomes stalled on a truncated mRNA and tag the nascent polypeptide for degradation. We used cryo-electron microscopy to...
3.
Schmied W, Tnimov Z, Uttamapinant C, Rae C, Fried S, Chin J
Nature
. 2018 Dec;
564(7736):444-448.
PMID: 30518861
Orthogonal ribosomes are unnatural ribosomes that are directed towards orthogonal messenger RNAs in Escherichia coli, through an altered version of the 16S ribosomal RNA of the small subunit. Directed evolution...