Christopher D Ma
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Explore the profile of Christopher D Ma including associated specialties, affiliations and a list of published articles.
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11
Citations
47
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Recent Articles
1.
Ma C, Faust D, Bonkovsky H
JIMD Rep
. 2023 Mar;
64(2):146-149.
PMID: 36873084
A 47-year-old woman with acute intermittent porphyria (AIP) has had recurring symptoms after achieving biochemical normalization of her urinary 5-aminolevulinic acid (ALA), porphobilinogen (PBG), and total porphyrins with givosiran. She...
2.
Bonkovsky H, Rudnick S, Ma C, Overbey J, Wang K, Faust D, et al.
Dig Dis Sci
. 2023 Feb;
68(6):2738-2746.
PMID: 36811718
Background And Aims: Chronic hepatitis C [CHC] is a risk factor for porphyria cutanea tarda [PCT]. To assess whether ledipasvir/sofosbuvir is effective for treating both PCT and CHC, we treated...
3.
Ma C, Faust D, Bonkovsky H
Mol Genet Metab Rep
. 2022 Dec;
34:100946.
PMID: 36578356
A 39-year-old woman with biochemically and clinically active acute intermittent porphyria (AIP) developed moderately severe liver injury after receiving her second dose of givosiran. Serologic evaluation ruled out hepatitis caused...
4.
Kanai T, Hu Z, Yang R, Wu W, Wang Z, Ma C, et al.
J Virol
. 2022 Dec;
97(1):e0178822.
PMID: 36519897
Despite the development of highly effective hepatitis C virus (HCV) treatments, an effective prophylactic vaccine is still lacking. HCV infection is mediated by its envelope glycoproteins, E1 and E2, during...
5.
Ma C, Bonkovsky H
Front Pharmacol
. 2022 Sep;
13:953961.
PMID: 36147354
Eslicarbazepine acetate, a third-generation antiepileptic drug (AED), has shown improved clinical response and safety in comparison to older generation AEDs for patients with partial-onset seizures. It is currently not known...
6.
Ma C, Bonkovsky H
Mol Genet Metab Rep
. 2022 Sep;
33:100915.
PMID: 36105850
Elagolix is an FDA-approved treatment for moderate-to-severe pain associated with endometriosis but has been associated with increased acute porphyric attacks in women with the acute hepatic porphyrias (AHPs). A fluorescence-based...
7.
Majeed C, Ma C, Xiao T, Rudnick S, Bonkovsky H
Drug Des Devel Ther
. 2022 Jun;
16:1827-1845.
PMID: 35734365
Small interfering ribonucleic acids [siRNAs] are short ribonucleic acid (RNA) fragments cleaved from double-stranded RNA molecules that target and bind to specific sequences on messenger RNA (mRNA), leading to their...
8.
Park S, Uchida T, Tilson S, Hu Z, Ma C, Leek M, et al.
Mol Ther Nucleic Acids
. 2022 May;
28:656-669.
PMID: 35615005
The CRISPR-Cas9 system has emerged as a powerful and efficient tool for genome editing. An important drawback of the CRISPR-Cas9 system is the constitutive endonuclease activity when Cas9 endonuclease and...
9.
Ma C, Van Horn C, Wan M, Bishop C, Bonkovsky H
Pharmacol Res Perspect
. 2022 Apr;
10(3):e00951.
PMID: 35445802
Compounds that induce 5-aminolevulinic acid [ALA] synthase-1 and/or cytochromes P-450 may induce acute porphyric attacks in patients with the acute hepatic porphyrias [AHPs]. Currently, there is no simple, robust model...
10.
Ma C, Imamura M, Talley D, Rolt A, Xu X, Wang A, et al.
Nat Microbiol
. 2020 Sep;
5(12):1532-1541.
PMID: 32868923
Fluoxazolevir is an aryloxazole-based entry inhibitor of hepatitis C virus (HCV). We show that fluoxazolevir inhibits fusion of HCV with hepatic cells by binding HCV envelope protein 1 to prevent...