Herbert L Bonkovsky
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Explore the profile of Herbert L Bonkovsky including associated specialties, affiliations and a list of published articles.
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230
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9013
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Recent Articles
1.
Halegoua-DeMarzio D, Navarro V, Davis A, Ahmad J, Avula B, Barnhart H, et al.
Drug Saf
. 2024 Oct;
48(2):143-150.
PMID: 39354283
Background: The attribution of drug-induced liver injury (DILI) to specific herbal and dietary supplements (HDS) is confounded by inaccurate labels and undisclosed ingredients. The US Drug-Induced Liver Injury Network (DILIN)...
2.
Soufleris S, Moore M, Phillips J, Netzel B, Rudnick S, Faust D, et al.
AME Case Rep
. 2024 Aug;
8:67.
PMID: 39091564
Background: Porphyria cutanea tarda (PCT) is usually caused by acquired defects in uroporphyrinogen decarboxylase (UROD) activity in the liver. This more common form of PCT is called type 1 PCT....
3.
Belot A, Puy H, Hamza I, Bonkovsky H
Liver Int
. 2024 Jun;
44(9):2235-2250.
PMID: 38888238
Heme is a primordial macrocycle upon which most aerobic life on Earth depends. It is essential to the survival and health of nearly all cells, functioning as a prosthetic group...
4.
Masood U, Venturini N, Nicoletti P, Dellinger A, Kleiner D, Bonkovsky H, et al.
Obstet Gynecol
. 2024 Apr;
143(6):819-823.
PMID: 38626448
There are limited data on the causative agents and characteristics of drug-induced liver injury in pregnant individuals. Data from patients with drug-induced liver injury enrolled in the ongoing multicenter Drug-Induced...
5.
Bonkovsky H, Ghabril M, Nicoletti P, Dellinger A, Fontana R, Barnhart H, et al.
Liver Int
. 2024 Mar;
44(6):1409-1421.
PMID: 38451034
Objective: To describe patients with NSAID-DILI, including genetic factors associated with idiosyncratic DILI. Methods: In DILIN, subjects with presumed DILI are enrolled and followed for at least 6 months. Causality...
6.
Madigan K, Rudnick S, Agnew M, Urooj N, Bonkovsky H
Pharmaceuticals (Basel)
. 2024 Jan;
17(1).
PMID: 38256864
Erythropoietic protoporphyria (EPP) is a genetic disorder stemming from reduced ferrochelatase expression, the final enzyme in the pathway of heme biosynthesis. A closely related condition, X-linked protoporphyria (XLP), bears similar...
7.
Thapar M, Singh A, Robinson K, Bonkovsky H
Clin Exp Gastroenterol
. 2024 Jan;
17:1-8.
PMID: 38205357
Porphyrias are, for the most part, inherited disorders of the heme biosynthetic pathway which lead to accumulation of specific intermediates responsible for most of the symptoms and signs of biochemically...
8.
Kuter D, Bonkovsky H, Monroy S, Ross G, Guillen-Navarro E, Cappellini M, et al.
J Hepatol
. 2023 Jul;
79(5):1150-1158.
PMID: 37479139
Background & Aims: Acute hepatic porphyria (AHP) is caused by defects in hepatic heme biosynthesis, leading to disabling acute neurovisceral attacks and chronic symptoms. In ENVISION (NCT03338816), givosiran treatment for...
9.
Barritt 4th A, Barnhart H, Gu J, Dellinger A, Rudnick S, Bonkovsky H
Am J Gastroenterol
. 2023 Jun;
118(12):2301-2304.
PMID: 37311048
Introduction: Diagnosis of drug-induced liver injury (DILI) is difficult. We reviewed cases in the DILI Network prospective study that were adjudicated to have liver injury due to other causes to...
10.
Balwani M, Bonkovsky H, Levy C, Anderson K, Bissell D, Parker C, et al.
N Engl J Med
. 2023 Apr;
388(15):1376-1385.
PMID: 37043653
Background: Erythropoietic protoporphyria and X-linked protoporphyria are inborn errors of heme biosynthesis that cause elevated circulating levels of metal-free protoporphyrin and phototoxicity. Both disorders are characterized by excruciating phototoxic attacks...