Christopher D Gregory
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Explore the profile of Christopher D Gregory including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
1980
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Recent Articles
11.
Jandl K, Gregory C, Kwapiszewska G
Am J Respir Cell Mol Biol
. 2018 Jun;
59(4):407-409.
PMID: 29924940
No abstract available.
12.
Gregory C, Dransfield I
Front Immunol
. 2018 Jun;
9:1111.
PMID: 29875772
Cells undergoing apoptosis produce heterogeneous populations of membrane delimited extracellular vesicles (Apo-EVs) which vary not only in size-from tens of nanometers to several microns-but also in molecular composition and cargo....
13.
Campana L, Starkey Lewis P, Pellicoro A, Aucott R, Man J, ODuibhir E, et al.
J Immunol
. 2017 Dec;
200(3):1169-1187.
PMID: 29263216
The disposal of apoptotic bodies by professional phagocytes is crucial to effective inflammation resolution. Our ability to improve the disposal of apoptotic bodies by professional phagocytes is impaired by a...
14.
Gregory C, Paterson M
Philos Trans R Soc Lond B Biol Sci
. 2017 Nov;
373(1737).
PMID: 29158317
The cell-death programme, apoptosis, is well established as a tumour suppressor mechanism. Paradoxically, high levels of apoptosis in tumours are closely coupled with poor prognosis. Indeed, where it has been...
15.
Lynch C, Panagopoulou M, Gregory C
Front Immunol
. 2017 Oct;
8:1174.
PMID: 29018443
It is known that apoptotic cells can have diverse effects on the tumor microenvironment. Emerging evidence indicates that, despite its renowned role in tumor suppression, apoptosis may also promote oncogenic...
16.
Voss J, Ford C, Petrova S, Melville L, Paterson M, Pound J, et al.
Cell Death Differ
. 2017 Feb;
24(6):971-983.
PMID: 28157210
In aggressive non-Hodgkin's lymphoma (NHL), constitutive apoptosis of a proportion of the tumor cell population can promote net tumor growth. This is associated with the accumulation of tumor-associated macrophages (TAMs)...
17.
Subiros-Funosas R, Mendive-Tapia L, Sot J, Pound J, Barth N, Varela Y, et al.
Chem Commun (Camb)
. 2016 Dec;
53(5):945-948.
PMID: 28009021
The rational design and synthesis of a Trp-BODIPY cyclic peptide for the fluorescent labelling of apoptotic bodies is described. Affinity assays, confocal microscopy and flow cytometry analysis confirmed the binding...
18.
Gregory C, Ford C, Voss J
Adv Exp Med Biol
. 2016 Aug;
930:51-88.
PMID: 27558817
Although apoptosis is well recognized as a cell death program with clear anticancer roles, accumulating evidence linking apoptosis with tissue repair and regeneration indicates that its relationship with malignant disease...
19.
Oosthuyzen W, Scullion K, Ivy J, Morrison E, Hunter R, Starkey Lewis P, et al.
J Am Soc Nephrol
. 2016 Mar;
27(11):3345-3355.
PMID: 27020854
Extracellular vesicles (ECVs) facilitate intercellular communication along the nephron, with the potential to change the function of the recipient cell. However, it is not known whether this is a regulated...
20.
Ford C, Petrova S, Pound J, Voss J, Melville L, Paterson M, et al.
Curr Biol
. 2015 Feb;
25(5):577-88.
PMID: 25702581
Background: Cells undergoing apoptosis are known to modulate their tissue microenvironments. By acting on phagocytes, notably macrophages, apoptotic cells inhibit immunological and inflammatory responses and promote trophic signaling pathways. Paradoxically,...