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Christopher Cheadle

Explore the profile of Christopher Cheadle including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 461
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Recent Articles
1.
Mecoli C, Talbot Jr C, Fava A, Cheadle C, Boin F, Wigley F, et al.
Arthritis Care Res (Hoboken) . 2019 Apr; 72(6):761-767. PMID: 31008568
Objective: Scleromyxedema (SMX) is a rare systemic sclerosis mimic that often responds to intravenous immunoglobulin (IVIG) therapy, yet the resulting clinical and biochemical changes have not been well characterized. To...
2.
Kolosova I, Angelini D, Fan C, Skinner J, Cheadle C, Johns R
Stem Cells Dev . 2012 Aug; 22(2):239-47. PMID: 22891677
Resistin-like molecule α (RELMα) is highly upregulated in the lungs of mice subjected to hypoxia. It is secreted from pulmonary epithelium and causes potent mitogenic, angiogenic, and vasoconstrictive effects in...
3.
Podowski M, Calvi C, Metzger S, Misono K, Poonyagariyagorn H, Lopez-Mercado A, et al.
J Clin Invest . 2011 Dec; 122(1):229-40. PMID: 22182843
Chronic obstructive pulmonary disease (COPD) is a prevalent smoking-related disease for which no disease-altering therapies currently exist. As dysregulated TGF-β signaling associates with lung pathology in patients with COPD and...
4.
Ji H, Wu G, Zhan X, Nolan A, Koh C, De Marzo A, et al.
PLoS One . 2011 Nov; 6(10):e26057. PMID: 22039435
The functions of key oncogenic transcription factors independent of context have not been fully delineated despite our richer understanding of the genetic alterations in human cancers. The MYC oncogene, which...
5.
Calvi C, Podowski M, DAlessio F, Metzger S, Misono K, Poonyagariyagorn H, et al.
PLoS One . 2011 Jun; 6(6):e20712. PMID: 21713037
Background: Respiratory dysfunction is a major contributor to morbidity and mortality in aged populations. The susceptibility to pulmonary insults is attributed to "low pulmonary reserve", ostensibly reflecting a combination of...
6.
Tsang K, Starost M, Nesterova M, Boikos S, Watkins T, Almeida M, et al.
Proc Natl Acad Sci U S A . 2010 Apr; 107(19):8683-8. PMID: 20421483
A population of stromal cells that retains osteogenic capacity in adult bone (adult bone stromal cells or aBSCs) exists and is under intense investigation. Mice heterozygous for a null allele...
7.
Zhao Y, Garcia J, Kolp L, Cheadle C, Rodriguez A, Vlahos N
Fertil Steril . 2010 Mar; 94(6):2264-71. PMID: 20226447
Objective: To evaluate the impact of two different luteal phase support protocols on gene expression of extracellular matrix (ECM) proteins and adhesion molecules in the human endometrium. Design: Eighty-four ECM...
8.
Aggarwal N, DAlessio F, Tsushima K, Sidhaye V, Cheadle C, Grigoryev D, et al.
Physiol Genomics . 2009 Dec; 41(2):109-19. PMID: 20028937
In animal models of acute lung injury (ALI), gene expression studies have focused on the acute phase of illness, with little emphasis on resolution. In this study, the acute phase...
9.
Podowski M, Calvi C, Cheadle C, Tuder R, Biswals S, Neptune E
Am J Pathol . 2009 Jun; 175(1):84-96. PMID: 19541933
Alveolar enlargement, which is characteristic of bronchopulmonary dysplasia, congenital matrix disorders, and cigarette smoke-induced emphysema, is thought to result from enhanced inflammation and ensuing excessive matrix proteolysis. Although there is...
10.
Finigan J, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae H, et al.
Am J Physiol Lung Cell Mol Physiol . 2009 Apr; 296(6):L1002-11. PMID: 19363121
The coagulation system is central to the pathophysiology of acute lung injury. We have previously demonstrated that the anticoagulant activated protein C (APC) prevents increased endothelial permeability in response to...