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Christopher B Highley

Explore the profile of Christopher B Highley including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 1453
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Recent Articles
1.
Claxton N, Luse M, Isakson B, Highley C
ACS Biomater Sci Eng . 2024 Nov; 10(12):7594-7605. PMID: 39585331
Advancing three-dimensional (3D) tissue constructs is central to creating models and engineered tissues that recapitulate biology. Materials that are permissive to cellular behaviors, including proliferation, morphogenesis of multicellular structures, and...
2.
Whitewolf J, Highley C
J Mater Chem B . 2024 Jul; 12(29):7122-7134. PMID: 38946474
Micro- and nanoencapsulation of cells has been studied as a strategy to protect cells from environmental stress and promote survival during delivery. Hydrogels used in encapsulation can be modified to...
3.
Miller B, Wolfe W, Gentry J, Grewal M, Highley C, De Vita R, et al.
Adv Healthc Mater . 2023 May; 12(22):e2300086. PMID: 37220996
Uterosacral ligament suspension (USLS) is a common surgical treatment for pelvic organ prolapse (POP). However, the relatively high failure rate of up to 40% underscores a strong clinical need for...
4.
Grewal M, Gray V, Letteri R, Highley C
Biomater Sci . 2021 Jun; 9(12):4374-4387. PMID: 34076655
The ability to spatiotemporally control the presentation of relevant biomolecules in synthetic culture systems has gained significant attention as researchers strive to recapitulate the endogenous extracellular matrix (ECM) in vitro....
5.
Miller B, Hansrisuk A, Highley C, Caliari S
ACS Biomater Sci Eng . 2021 Apr; 7(9):4164-4174. PMID: 33891397
The fibrous architecture of the extracellular matrix (ECM) is recognized as an integral regulator of cell function. However, there is an unmet need to develop mechanically robust biomaterials mimicking nanofibrous...
6.
Grewal M, Highley C
Biomater Sci . 2021 Feb; 9(12):4228-4245. PMID: 33522527
The extracellular matrix (ECM) is a water-swollen, tissue-specific material environment in which biophysiochemical signals are organized and influence cell behaviors. Electrospun nanofibrous substrates have been pursued as platforms for tissue...
7.
Ouyang L, Highley C, Rodell C, Sun W, Burdick J
ACS Biomater Sci Eng . 2021 Jan; 2(10):1743-1751. PMID: 33440472
The development of printable biomaterial inks is critical to the application of 3D printing in biomedicine. To print high-resolution structures with fidelity to a computer-aided design, materials used in 3D...
8.
Pfaff B, Pruett L, Cornell N, de Rutte J, Di Carlo D, Highley C, et al.
ACS Biomater Sci Eng . 2021 Jan; 7(2):422-427. PMID: 33423459
Microporous annealed particle (MAP) scaffolds consist of a slurry of hydrogel microspheres that undergo annealing to form a solid scaffold. MAP scaffolds have contained functional groups with dual abilities to...
9.
McCormack A, Highley C, Leslie N, Melchels F
Trends Biotechnol . 2020 Jan; 38(6):584-593. PMID: 31955894
Extrusion-based 3D printers have been adopted in pursuit of engineering functional tissues through 3D bioprinting. However, we are still a long way from the promise of fabricating constructs approaching the...
10.
Highley C, Song K, Daly A, Burdick J
Adv Sci (Weinh) . 2019 Jan; 6(1):1801076. PMID: 30643716
3D printing involves the development of inks that exhibit the requisite properties for both printing and the intended application. In bioprinting, these inks are often hydrogels with controlled rheological properties...