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Jason A Burdick

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Articles 300
Citations 15567
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Recent Articles
1.
Lee S, Li Z, Zhang E, Kim D, Huang Z, Heo Y, et al.
Bioact Mater . 2025 Mar; 48:400-413. PMID: 40083776
Meniscus injuries present significant therapeutic challenges due to their limited self-healing capacity and the diverse biological and mechanical properties across the tissue. Conventional repair strategies do not replicate the complex...
2.
Solsona-Pujol A, Di Caprio N, Zlotnick H, Davidson M, Riffe M, Burdick J
J Biomed Mater Res A . 2025 Mar; 113(3):e37889. PMID: 40033794
Hydrogels are an important class of biomaterials that are being developed for use in medicine, such as in drug delivery and tissue engineering applications. To improve properties (e.g., injectability, nutrient...
3.
Uman S, Weingarten N, Helmers M, Iyengar A, Xu K, Worthington K, et al.
Adv Nanobiomed Res . 2025 Feb; 4(11). PMID: 39957840
Extracellular vesicles (EVs) are gaining interest in regenerative medicine and biomaterials have been shown to extend EV bioavailability following delivery. Here, we report the labeling of both hydrogels and EVs...
4.
Di Caprio N, Hughes A, Burdick J
Sci Adv . 2025 Jan; 11(3):eadq5011. PMID: 39823334
Tissues form during development through mechanical compaction of their extracellular matrix (ECM) and shape morphing, processes that result in complex-shaped structures that contribute to tissue function. While observed in vivo,...
5.
Lee J, Kirkpatrick B, Dhand A, Hibbard L, Nelson B, Skillin N, et al.
J Mater Chem B . 2024 Dec; 13(3):894-903. PMID: 39648868
Covalent hydrogel networks suffer from a stiffness-toughness conflict, where increased crosslinking density enhances the modulus of the material but also leads to embrittlement and diminished extensibility. Recently, strategies have been...
6.
Gordian-Velez W, Browne K, Galarraga J, Chouhan D, Duda J, Espana R, et al.
Adv Healthc Mater . 2024 Nov; 14(2):e2402997. PMID: 39494983
Parkinson's disease is characterized by motor deficits emerging from insufficient dopamine in the striatum after degeneration of dopaminergic neurons and their long-projecting axons comprising the nigrostriatal pathway. To address this,...
7.
Nakamura K, Di Caprio N, Burdick J
Adv Mater . 2024 Oct; 36(47):e2410661. PMID: 39358935
4D printing of hydrogels is an emerging technology used to fabricate shape-morphing soft materials that are responsive to external stimuli for use in soft robotics and biomedical applications. Soft materials...
8.
Stewart D, Brisson B, Dekky B, Berger A, Yen W, Mauldin E, et al.
NPJ Breast Cancer . 2024 Oct; 10(1):86. PMID: 39358397
Collagen plays a critical role in regulating breast cancer progression and therapeutic resistance. An improved understanding of both the features and drivers of tumor-permissive and -restrictive collagen matrices are critical...
9.
Lee S, Li Z, Zhang E, Kim D, Huang Z, Lee S, et al.
bioRxiv . 2024 Sep; PMID: 39345590
Meniscus injuries present significant therapeutic challenges due to their limited self-healing capacity and diverse biological and mechanical properties across meniscal tissue. Conventional repair strategies neglect to replicate the complex zonal...
10.
Kirkpatrick B, Hach G, Nelson B, Skillin N, Lee J, Hibbard L, et al.
Adv Mater . 2024 Sep; 36(46):e2409603. PMID: 39340292
Hydrogels are often synthesized through photoinitiated step-, chain-, and mixed-mode polymerizations, generating diverse network topologies and resultant material properties that depend on the underlying network connectivity. While many photocrosslinking reactions...