Christoph Roesli
Overview
Explore the profile of Christoph Roesli including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
356
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Recent Articles
1.
Simeoni P, Deissler M, Bienert R, Gritsch M, Nerkamp J, Kirsch S, et al.
Biotechnol Bioeng
. 2023 Aug;
120(11):3299-3310.
PMID: 37526307
Quality by Design (QbD) principles play an increasingly important role in the pharmaceutical industry. Here, we used an analytical QbD (AQbD) approach to develop a capillary electrophoresis sodium dodecyl sulfate...
2.
Ruprecht B, Roesli C, Lemeer S, Kuster B
Proteomics
. 2016 Mar;
16(10):1447-56.
PMID: 26990019
Phosphorylation is a reversible posttranslational protein modification which plays a pivotal role in intracellular signaling. Despite extensive efforts, phosphorylation site mapping of proteomes is still incomplete motivating the exploration of...
3.
Nadler W, Berg R, Walch P, Hanke S, Baalmann M, Kerner A, et al.
Anal Bioanal Chem
. 2015 Oct;
408(8):2055-67.
PMID: 26493978
Cysteine is unique among the proteinogenic amino acids due to its ability to form disulfide bonds. While this property is of vital importance for protein structures and biological processes, it...
4.
Roesli C
Expert Rev Proteomics
. 2014 Nov;
12(1):5-8.
PMID: 25407217
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a median overall survival of 6 months. Late diagnosis due to the absence of specific symptoms during disease development, in addition...
5.
Strassberger V, Gutbrodt K, Krall N, Roesli C, Takizawa H, Manz M, et al.
J Proteomics
. 2014 Feb;
99:138-51.
PMID: 24487095
Biological Significance: The ability to discriminate between malignant and healthy, essential cells represents an important requirement for the development of armed antibodies for the therapy of hematological malignancies. Our proteomic...
6.
Benk A, Roesli C
Anal Bioanal Chem
. 2012 Feb;
404(4):1039-56.
PMID: 22358999
Profound knowledge of protein abundances in healthy tissues and their changes in disease is crucial for understanding biological processes in basic science and for the development of novel diagnostics and...
7.
Fugmann T, Borgia B, Revesz C, Godo M, Forsblom C, Hamar P, et al.
Kidney Int
. 2011 May;
80(3):272-81.
PMID: 21544065
At present, the urinary albumin excretion rate is the best noninvasive predictor for diabetic nephropathy (DN) but major limitations are associated with this marker. Here, we used in vivo perfusion...
8.
Roesli C, Fugmann T, Borgia B, Schliemann C, Neri D, Jucker M
J Proteomics
. 2011 Jan;
74(4):539-46.
PMID: 21262399
Assessing protein changes in the cerebral vasculature of brain disorders may increase our understanding of disease pathogenesis and facilitate diagnostic and therapeutic intervention. By combining perfusion of mice with a...
9.
Strassberger V, Trussel S, Fugmann T, Neri D, Roesli C
Proteomics
. 2010 Sep;
10(19):3544-8.
PMID: 20821733
The in vivo perfusion of rodent models of disease with biotin derivatives and the subsequent comparative proteomic analysis of healthy and diseased tissues represent a promising methodology for the identification...
10.
Sommavilla R, Pasche N, Trachsel E, Giovannoni L, Roesli C, Villa A, et al.
Protein Eng Des Sel
. 2010 Jun;
23(8):653-61.
PMID: 20551083
Proinflammatory cytokines have been used for several years in patients with advanced cancer but their administration is typically associated with severe toxicity hampering their application to therapeutically active regimens. This...