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Christoph Kroner

Explore the profile of Christoph Kroner including associated specialties, affiliations and a list of published articles. Areas
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Citations 379
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Recent Articles
1.
Lopez J, Powles T, Braiteh F, Siu L, LoRusso P, Friedman C, et al.
Nat Med . 2025 Jan; 31(1):152-164. PMID: 39762422
Effective targeting of somatic cancer mutations to enhance the efficacy of cancer immunotherapy requires an individualized approach. Autogene cevumeran is a uridine messenger RNA lipoplex-based individualized neoantigen-specific immunotherapy designed from...
2.
Vogel A, Kanevsky I, Che Y, Swanson K, Muik A, Vormehr M, et al.
Nature . 2021 Feb; 592(7853):283-289. PMID: 33524990
A safe and effective vaccine against COVID-19 is urgently needed in quantities that are sufficient to immunize large populations. Here we report the preclinical development of two vaccine candidates (BNT162b1...
3.
Kroner C, Thunemann M, Vollmer S, Kinzer M, Feil R, Richert C
Angew Chem Int Ed Engl . 2014 Jul; 53(35):9198-202. PMID: 25045108
It is becoming increasingly clear that nature uses RNAs extensively for regulating vital functions of the cell, and short sequences are frequently used to suppress gene expression. However, controlling the...
4.
Kroner C, Gockel A, Liu W, Richert C
Chemistry . 2013 Nov; 19(47):15879-87. PMID: 24194407
Cofactors are pivotal compounds for the cell and many biotechnological processes. It is therefore interesting to ask how well cofactors can be bound by oligonucleotides designed not to convert but...
5.
Kroner C, Rothlingshofer M, Richert C
J Org Chem . 2011 Mar; 76(8):2933-6. PMID: 21413744
Gaps in the central strand of oligonucleotide triplexes bind nucleoside phosphates tightly. Watson-Crick and Hoogsteen base pairing as design principle yield motifs with high affinity for nucleoside phosphates with A...