Christoph J Burckhardt
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Explore the profile of Christoph J Burckhardt including associated specialties, affiliations and a list of published articles.
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21
Citations
1058
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Recent Articles
1.
Burckhardt C, Minna J, Danuser G
STAR Protoc
. 2021 Jul;
2(3):100644.
PMID: 34278331
Co-immunoprecipitation (co-IP) of protein complexes from cell lysates is widely used to study protein-protein interactions. However, establishing robust co-IP assays often involves considerable optimization. Moreover, co-IP results are frequently presented...
2.
Burckhardt C, Minna J, Danuser G
Dev Cell
. 2021 Mar;
56(8):1164-1181.e12.
PMID: 33761321
Cells probe their surrounding matrix for attachment sites via integrins that are internalized by endocytosis. We find that SH3BP4 regulates integrin surface expression in a signaling-dependent manner via clathrin-coated pits...
3.
Park J, Burckhardt C, Lazcano R, Solis L, Isogai T, Li L, et al.
Nature
. 2020 Feb;
578(7796):621-626.
PMID: 32051585
The mechanics of the cellular microenvironment continuously modulates cell functions such as growth, survival, apoptosis, differentiation and morphogenesis via cytoskeletal remodelling and actomyosin contractility. Although all of these processes consume...
4.
Srinivasan S, Burckhardt C, Bhave M, Chen Z, Chen P, Wang X, et al.
PLoS Biol
. 2018 Apr;
16(4):e2005377.
PMID: 29668686
Dynamin Guanosine Triphosphate hydrolases (GTPases) are best studied for their role in the terminal membrane fission process of clathrin-mediated endocytosis (CME), but they have also been proposed to regulate earlier...
5.
Wang I, Burckhardt C, Yakimovich A, Greber U
Viruses
. 2018 Apr;
10(4).
PMID: 29614729
Viruses have a dual nature: particles are “passive substances” lacking chemical energy transformation, whereas infected cells are “active substances” turning-over energy. How passive viral substances convert to active substances, comprising...
6.
Wang I, Burckhardt C, Yakimovich A, Morf M, Greber U
J Cell Sci
. 2017 May;
130(13):2185-2195.
PMID: 28515232
Transport of large cargo through the cytoplasm requires motor proteins and polarized filaments. Viruses that replicate in the nucleus of post-mitotic cells use microtubules and the dynein-dynactin motor to traffic...
7.
Costigliola N, Ding L, Burckhardt C, Han S, Gutierrez E, Mota A, et al.
Proc Natl Acad Sci U S A
. 2017 May;
114(20):5195-5200.
PMID: 28465431
The intermediate filament vimentin is required for cells to transition from the epithelial state to the mesenchymal state and migrate as single cells; however, little is known about the specific...
8.
Gan Z, Ding L, Burckhardt C, Lowery J, Zaritsky A, Sitterley K, et al.
Cell Syst
. 2016 Nov;
3(5):500-501.
PMID: 27883892
No abstract available.
9.
Gan Z, Ding L, Burckhardt C, Lowery J, Zaritsky A, Sitterley K, et al.
Cell Syst
. 2016 Sep;
3(3):252-263.e8.
PMID: 27667364
Increased expression of vimentin intermediate filaments (VIFs) enhances directed cell migration, but the mechanism behind VIFs' effect on motility is not understood. VIFs interact with microtubules, whose organization contributes to...
10.
Ingold E, Vom Berg-Maurer C, Burckhardt C, Lehnherr A, Rieder P, Keller P, et al.
Biol Open
. 2015 Jan;
4(2):146-54.
PMID: 25572423
The formation of functional neuronal circuits relies on accurate migration and proper axonal outgrowth of neuronal precursors. On the route to their targets migrating cells and growing axons depend on...