Christoph Fritzsch
Overview
Explore the profile of Christoph Fritzsch including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
377
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0
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Recent Articles
1.
Fritzsch C, Baumgartner S, Kuban M, Steinshorn D, Reid G, Legewie S
Mol Syst Biol
. 2018 Feb;
14(2):e7678.
PMID: 29476006
Cellular decision-making and environmental adaptation are dependent upon a heterogeneous response of gene expression to external cues. Heterogeneity arises in transcription from random switching between transcriptionally active and inactive states,...
2.
Larson D, Fritzsch C, Sun L, Meng X, Lawrence D, Singer R
Elife
. 2013 Sep;
2:e00750.
PMID: 24069527
Single-cell analysis has revealed that transcription is dynamic and stochastic, but tools are lacking that can determine the mechanism operating at a single gene. Here we utilize single-molecule observations of...
3.
Pinheiro I, Margueron R, Shukeir N, Eisold M, Fritzsch C, Richter F, et al.
Cell
. 2012 Sep;
150(5):948-60.
PMID: 22939622
Heterochromatin serves important functions, protecting genome integrity and stabilizing gene expression programs. Although the Suv39h methyltransferases (KMTs) are known to ensure pericentric H3K9me3 methylation, the mechanisms that initiate and maintain...
4.
Eulalio A, Helms S, Fritzsch C, Fauser M, Izaurralde E
RNA
. 2009 Apr;
15(6):1067-77.
PMID: 19383769
Proteins of the GW182 family are essential for miRNA-mediated gene silencing in animal cells; they interact with Argonaute proteins (AGOs) and are required for both the translational repression and mRNA...