Christine Cavalcanti-Proenca
Overview
Explore the profile of Christine Cavalcanti-Proenca including associated specialties, affiliations and a list of published articles.
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17
Citations
5538
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Recent Articles
1.
Dastani Z, Hivert M, Timpson N, Perry J, Yuan X, Scott R, et al.
PLoS Genet
. 2012 Apr;
8(3):e1002607.
PMID: 22479202
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a...
2.
Palmer N, McDonough C, Hicks P, Roh B, Wing M, An S, et al.
PLoS One
. 2012 Jan;
7(1):e29202.
PMID: 22238593
African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity. The aim of this study was to...
3.
Kilpelainen T, Qi L, Brage S, Sharp S, Sonestedt E, Demerath E, et al.
PLoS Med
. 2011 Nov;
8(11):e1001116.
PMID: 22069379
Background: The FTO gene harbors the strongest known susceptibility locus for obesity. While many individual studies have suggested that physical activity (PA) may attenuate the effect of FTO on obesity...
4.
Schumann G, Coin L, Lourdusamy A, Charoen P, Berger K, Stacey D, et al.
Proc Natl Acad Sci U S A
. 2011 Apr;
108(17):7119-24.
PMID: 21471458
Alcohol consumption is a moderately heritable trait, but the genetic basis in humans is largely unknown, despite its clinical and societal importance. We report a genome-wide association study meta-analysis of...
5.
Speliotes E, Willer C, Berndt S, Monda K, Thorleifsson G, Jackson A, et al.
Nat Genet
. 2010 Oct;
42(11):937-48.
PMID: 20935630
Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined associations between body mass index and...
6.
Heid I, Jackson A, Randall J, Winkler T, Qi L, Steinthorsdottir V, et al.
Nat Genet
. 2010 Oct;
42(11):949-60.
PMID: 20935629
Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic consequences independent of overall adiposity. WHR is heritable, but few genetic variants influencing this trait...
7.
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson A, et al.
Nat Genet
. 2010 Jan;
42(2):105-16.
PMID: 20081858
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide association studies informative for fasting glucose, fasting insulin and indices...
8.
Saxena R, Hivert M, Langenberg C, Tanaka T, Pankow J, Vollenweider P, et al.
Nat Genet
. 2010 Jan;
42(2):142-8.
PMID: 20081857
Glucose levels 2 h after an oral glucose challenge are a clinical measure of glucose tolerance used in the diagnosis of type 2 diabetes. We report a meta-analysis of nine...
9.
Rung J, Cauchi S, Albrechtsen A, Shen L, Rocheleau G, Cavalcanti-Proenca C, et al.
Nat Genet
. 2009 Sep;
41(10):1110-5.
PMID: 19734900
Genome-wide association studies have identified common variants that only partially explain the genetic risk for type 2 diabetes (T2D). Using genome-wide association data from 1,376 French individuals, we identified 16,360...
10.
Choquet H, Cavalcanti-Proenca C, Lecoeur C, Dina C, Cauchi S, Vaxillaire M, et al.
Hum Mol Genet
. 2009 Apr;
18(13):2495-501.
PMID: 19377085
A recent study reported an association between the brain natriuretic peptide (BNP) promoter T-381C polymorphism (rs198389) and protection against type 2 diabetes (T2D). As replication in several studies is mandatory...