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Christina Grigoriadou

Explore the profile of Christina Grigoriadou including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 322
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Recent Articles
1.
Cao M, Hussmann G, Tao Y, OConnor E, Parthemore C, Zhang-Hulsey D, et al.
Antibodies (Basel) . 2023 Nov; 12(4). PMID: 37987246
Asparagine deamidation is a post-translational modification (PTM) that converts asparagine residues into iso-aspartate and/or aspartate. Non-enzymatic asparagine deamidation is observed frequently during the manufacturing, processing, and/or storage of biotherapeutic proteins....
2.
Christian E, Hussmann G, Babu M, Prophet M, Mazor Y, Chen W, et al.
J Immunol Methods . 2021 Jul; 496:113099. PMID: 34224737
Bispecific antibodies (BsAbs) are engineered to simultaneously bind two different antigens, and offer promising clinical outcomes for various diseases. The dual binding properties of BsAbs may enable superior efficacies and/or...
3.
Qin H, Grigoriadou C, Cooperman B
Biochemistry . 2009 Apr; 48(22):4699-706. PMID: 19366171
Addition of an Escherichia coli 50S subunit (50S(Cy5)) containing a Cy5-labeled L11 N-terminal domain (L11-NTD) within the GTPase-associated center (GAC) to an E. coli 30S initiation complex (30SIC(Cy3)) containing Cy3-labeled...
4.
Liu J, HuangFu W, Kumar K, Qian J, Casey J, Hamanaka R, et al.
Cell Host Microbe . 2009 Jan; 5(1):72-83. PMID: 19154989
Phosphorylation-dependent ubiquitination and degradation of the IFNAR1 chain of the type I interferon (IFN) receptor is regulated by two different pathways, one of which is ligand independent. We report that...
5.
Bobrovnikova-Marjon E, Hatzivassiliou G, Grigoriadou C, Romero M, Cavener D, Thompson C, et al.
Proc Natl Acad Sci U S A . 2008 Oct; 105(42):16314-9. PMID: 18852460
The role of the endoplasmic reticulum stress-regulated kinase, PERK, in mammary gland function was assessed through generation of a targeted deletion in mammary epithelium. Characterization revealed that PERK is required...
6.
Grigoriadou C, Marzi S, Pan D, Gualerzi C, Cooperman B
J Mol Biol . 2007 Sep; 373(3):551-61. PMID: 17868695
IF3 has a fidelity function in the initiation of translation, inducing the dissociation of fMet-tRNA(fMet) from the 30 S initiation complexes (30SIC) containing a non-canonical initiation triplet (e.g. AUU) in...
7.
Grigoriadou C, Marzi S, Kirillov S, Gualerzi C, Cooperman B
J Mol Biol . 2007 Sep; 373(3):562-72. PMID: 17868692
Association of the 30 S initiation complex (30SIC) and the 50 S ribosomal subunit, leading to formation of the 70 S initiation complex (70SIC), is a critical step of the...