Christina Georgikou
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Explore the profile of Christina Georgikou including associated specialties, affiliations and a list of published articles.
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8
Citations
93
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Recent Articles
1.
Georgikou C, Buglioni L, Bremerich M, Roubicek N, Yin L, Gross W, et al.
Biomolecules
. 2020 May;
10(5).
PMID: 32429039
The naturally occurring isothiocyanate sulforaphane, found in vegetables, is promising in cancer treatment, e.g., by the normalization of enhanced levels of NF-κB-signaling in tumor stem cells. We chemically synthesized seven...
2.
Xiao X, Sticht C, Yin L, Liu L, Karakhanova S, Yin Y, et al.
Oncotarget
. 2020 Apr;
11(14):1203-1217.
PMID: 32292571
Food-derived plant microRNAs are suggested to control human genes by "cross-kingdom" regulation. We examined microRNAs in sprouts from , known as broccoletti, which are widely used as sulforaphane supplements, and...
3.
Georgikou C, Yin L, Gladkich J, Xiao X, Sticht C, de la Torre C, et al.
Cancer Lett
. 2019 Nov;
469:238-245.
PMID: 31678166
The therapy resistance of pancreatic cancer is associated with the loss of gap junction intercellular communication and connexin 43 expression. The broccoli isothiocyanate sulforaphane restored these features and therapy sensitivity....
4.
Yin L, Xiao X, Georgikou C, Luo Y, Liu L, Gladkich J, et al.
Mol Ther Oncolytics
. 2019 May;
14:74-81.
PMID: 31044154
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal tumors, with poor therapeutic options in the advanced state. The broccoli-derived anti-inflammatory agent sulforaphane was shown to inhibit the progression...
5.
Yin L, Xiao X, Georgikou C, Yin Y, Liu L, Karakhanova S, et al.
Cancer Lett
. 2019 Mar;
452:203-212.
PMID: 30910589
NF-κB contributes to the aggressiveness of pancreatic ductal adenocarcinoma (PDA), which is counteracted by the bioactive agent sulforaphane. We investigated sulforaphane-induced microRNA signaling and its influence on progression features. Using...
6.
Marz M, Meyer S, Erb U, Georgikou C, Horstmann M, Hetjens S, et al.
Leuk Res
. 2018 Jul;
71:47-54.
PMID: 30005184
Despite the high prevalence of central nervous system (CNS) involvement in relapsing pediatric acute lymphoblastic leukemia (ALL), our understanding of CNS invasion is still vague. As lymphoblasts have to overcome...
7.
Vincensini L, Blisnick T, Bertiaux E, Hutchinson S, Georgikou C, Ooi C, et al.
Biol Cell
. 2017 Nov;
110(2):33-47.
PMID: 29148062
Background Information: Eukaryotic cilia and flagella are sophisticated organelles composed of several hundreds of proteins that need to be incorporated at the right time and the right place during assembly....
8.
Ooi C, Rotureau B, Gribaldo S, Georgikou C, Julkowska D, Blisnick T, et al.
PLoS One
. 2015 Jul;
10(7):e0133676.
PMID: 26218532
African trypanosomes are flagellated parasites that cause sleeping sickness. Parasites are transmitted from one mammalian host to another by the bite of a tsetse fly. Trypanosoma brucei possesses three different...