Christian W Keller
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Explore the profile of Christian W Keller including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
1920
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Recent Articles
11.
Keller C, Pawlitzki M, Wiendl H, Lunemann J
Int J Mol Sci
. 2021 Jun;
22(11).
PMID: 34071155
(MG) is an autoimmune disease in which immunoglobulin G (IgG) antibodies (Abs) bind to acetylcholine receptors (AChR) or to functionally related molecules in the postsynaptic membrane at the neuromuscular junction....
12.
Deb-Chatterji M, Keller C, Koch S, Wiendl H, Gerloff C, Magnus T, et al.
Cells
. 2021 Jun;
10(5).
PMID: 34066885
Complement activation has been implicated in the pathogenesis of many vasculitic syndromes such as anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides. Using an array-based multiplex system, we simultaneously quantified serum and CSF...
13.
Keller C, Oechtering J, Wiendl H, Kappos L, Kuhle J, Lunemann J
Ann Clin Transl Neurol
. 2021 Mar;
8(4):944-950.
PMID: 33646629
We determined activation profiles of the classical and alternative complement pathway in 39 treatment-naïve patients with early relapse-onset MS. Plasma concentrations of complement fragments were unchanged in MS compared to...
14.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
15.
Srimat Kandadai K, Kotur M, Dokalis N, Amrein I, Keller C, Munz C, et al.
Autophagy
. 2021 Feb;
17(11):3566-3576.
PMID: 33522362
Microglia, resident myeloid immune cells of the central nervous system (CNS), actively shape the circuitry of the brain, maintain CNS homeostasis during the steady state and orchestrate immune responses upon...
16.
Caduff N, McHugh D, Murer A, Ramer P, Raykova A, Landtwing V, et al.
PLoS Pathog
. 2020 Dec;
16(12):e1009167.
PMID: 33347498
[This corrects the article DOI: 10.1371/journal.ppat.1008477.].
17.
Keller C, Munz C, Lunemann J
Trends Neurosci
. 2020 Oct;
43(12):1024-1033.
PMID: 33010946
The CNS accommodates a diverse myeloid immune cell compartment that maintains CNS homeostasis in the steady state while contributing to tissue injury during infectious, autoimmune, and neurodegenerative disease conditions. Autophagy...
18.
McHugh D, Myburgh R, Caduff N, Spohn M, Kok Y, Keller C, et al.
Life Sci Alliance
. 2020 Jun;
3(8).
PMID: 32576602
HIV and EBV are human pathogens that cause a considerable burden to worldwide health. In combination, these viruses are linked to AIDS-associated lymphomas. We found that EBV, which transforms B...
19.
Keller C, Kotur M, Mundt S, Dokalis N, Ligeon L, Shah A, et al.
Autophagy
. 2020 May;
17(5):1244-1258.
PMID: 32401602
Whereas central nervous system (CNS) homeostasis is highly dependent on tissue surveillance by immune cells, dysregulated entry of leukocytes during autoimmune neuroinflammation causes severe immunopathology and neurological deficits. To invade...
20.
Malhotra S, Costa C, Eixarch H, Keller C, Amman L, Martinez-Banaclocha H, et al.
Brain
. 2020 Apr;
143(5):1414-1430.
PMID: 32282893
Primary progressive multiple sclerosis is a poorly understood disease entity with no specific prognostic biomarkers and scarce therapeutic options. We aimed to identify disease activity biomarkers in multiple sclerosis by...