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Christian Umkehrer

Explore the profile of Christian Umkehrer including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 291
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Recent Articles
1.
Umkehrer C
Nat Rev Cancer . 2022 Apr; 22(6):321. PMID: 35459934
No abstract available.
2.
Haas L, Elewaut A, Gerard C, Umkehrer C, Leiendecker L, Pedersen M, et al.
Nat Cancer . 2022 Feb; 2(7):693-708. PMID: 35121945
How targeted therapies and immunotherapies shape tumors, and thereby influence subsequent therapeutic responses, is poorly understood. In the present study, we show, in melanoma patients and mouse models, that when...
3.
Umkehrer C, Holstein F, Formenti L, Jude J, Froussios K, Neumann T, et al.
Nat Biotechnol . 2020 Jul; 39(2):174-178. PMID: 32719478
We developed a functional lineage tracing tool termed CaTCH (CRISPRa tracing of clones in heterogeneous cell populations). CaTCH combines precise clonal tracing of millions of cells with the ability to...
4.
Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, et al.
Science . 2018 Apr; 360(6390):800-805. PMID: 29622725
Defining direct targets of transcription factors and regulatory pathways is key to understanding their roles in physiology and disease. We combined SLAM-seq [thiol(SH)-linked alkylation for the metabolic sequencing of RNA],...