Christian Sigler
Overview
Explore the profile of Christian Sigler including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
46
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Recent Articles
1.
Habringer S, Ihlow J, Kleo K, Klostermann A, Schmidt M, Chai L, et al.
Oncologist
. 2024 Jun;
29(10):908-912.
PMID: 38886160
A patient with gastrointestinal stroma tumor (GIST) and KIT p.V559D and BRAF p.G469A alterations was referred to our institutional molecular tumor board (MTB) to discuss therapeutic implications. The patient had...
2.
Benary M, Wang X, Schmidt M, Soll D, Hilfenhaus G, Nassir M, et al.
JAMA Netw Open
. 2023 Nov;
6(11):e2343689.
PMID: 37976064
Importance: Clinical interpretation of complex biomarkers for precision oncology currently requires manual investigations of previous studies and databases. Conversational large language models (LLMs) might be beneficial as automated tools for...
3.
Schossig P, Coskun E, Arsenic R, Horst D, Sehouli J, Bergmann E, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768616
Adoptive T cell-receptor therapy (ACT) could represent a promising approach in the targeted treatment of epithelial ovarian cancer (EOC). However, the identification of suitable tumor-associated antigens (TAAs) as targets is...
4.
Gyorffy B, Stelniec-Klotz I, Sigler C, Kasack K, Redmer T, Qian Y, et al.
Oncotarget
. 2015 Jun;
6(15):13334-46.
PMID: 26033452
Our understanding of oncogenic signaling pathways has strongly fostered current concepts for targeted therapies in metastatic colorectal cancer. The RALA pathway is novel candidate due to its independent role in...