Christian Rosenmund
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Explore the profile of Christian Rosenmund including associated specialties, affiliations and a list of published articles.
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Articles
131
Citations
8168
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Recent Articles
1.
Usher S, Toulme E, Florea R, Yatskevich S, Jao C, Dijkhof L, et al.
Sci Adv
. 2025 Mar;
11(11):eads6004.
PMID: 40085699
NALCN (sodium leak channel, nonselective) is vital for regulating electrical activity in neurons and other excitable cells, and mutations in the channel or its auxiliary proteins lead to severe neurodevelopmental...
2.
Rizo J, Jaczynska K, Rosenmund C
FEBS Open Bio
. 2025 Jan;
PMID: 39815397
Neurotransmitter release is triggered in microseconds by the two C domains of the Ca sensor synaptotagmin-1 and by SNARE complexes, which form four-helix bundles that bridge the vesicle and plasma...
3.
Kapucu G, Trimbuch T, Rosenmund C, Weber-Boyvat M
Methods Mol Biol
. 2025 Jan;
2887():281-294.
PMID: 39806162
The bimolecular fluorescence complementation (BiFC) technique is a powerful tool for visualizing protein-protein interactions in vivo. It involves genetically fused nonfluorescent fragments of green fluorescent protein (GFP) or its variants...
4.
Jaczynska K, Esser V, Xu J, Sari L, Lin M, Rosenmund C, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(1):e2417941121.
PMID: 39793049
Neurotransmitter release is triggered in microseconds by Ca-binding to the Synaptotagmin-1 C-domains and by SNARE complexes that form four-helix bundles between synaptic vesicles and plasma membranes, but the coupling mechanism...
5.
Kravcenko U, Ruwolt M, Kroll J, Yushkevich A, Zenkner M, Ruta J, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(49):e2407375121.
PMID: 39602275
Synaptic vesicles (SVs) store and transport neurotransmitters to the presynaptic active zone for release by exocytosis. After release, SV proteins and excess membrane are recycled via endocytosis, and new SVs...
6.
Toulme E, Lazaro A, Trimbuch T, Rizo J, Rosenmund C
Proc Natl Acad Sci U S A
. 2024 Oct;
121(42):e2409636121.
PMID: 39374398
The Ca sensor synaptotagmin-1 (Syt1) triggers neurotransmitter release together with the neuronal sensitive factor attachment protein receptor (SNARE) complex formed by syntaxin-1, SNAP25, and synaptobrevin. Moreover, Syt1 increases synaptic vesicle...
7.
Favier M, Martin Garcia E, Icick R, de Almeida C, Jehl J, Desplanque M, et al.
Nat Commun
. 2024 Jul;
15(1):5691.
PMID: 38971801
Cholinergic striatal interneurons (ChIs) express the vesicular glutamate transporter 3 (VGLUT3) which allows them to regulate the striatal network with glutamate and acetylcholine (ACh). In addition, VGLUT3-dependent glutamate increases ACh...
8.
Toulme E, Murach J, Barfuss S, Kroll J, Malsam J, Trimbuch T, et al.
J Neurosci
. 2024 Jul;
44(31).
PMID: 38951039
The release of neurotransmitters (NTs) at central synapses is dependent on a cascade of protein interactions, specific to the presynaptic compartment. Among those dedicated molecules, the cytosolic complexins play an...
9.
Toulme E, Lazaro A, Trimbuch T, Rizo J, Rosenmund C
bioRxiv
. 2024 Jul;
PMID: 38948868
The Ca sensor synaptotagmin-1 triggers neurotransmitter release together with the neuronal SNARE complex formed by syntaxin-1, SNAP25 and synaptobrevin. Moreover, synaptotagmin-1 increases synaptic vesicle priming and impairs spontaneous vesicle release....
10.
Jaczynska K, Esser V, Xu J, Sari L, Lin M, Rosenmund C, et al.
bioRxiv
. 2024 Jul;
PMID: 38948826
Neurotransmitter release is triggered in microseconds by Ca-binding to the Synaptotagmin-1 C domains and by SNARE complexes that form four-helix bundles between synaptic vesicles and plasma membranes, but the coupling...