Christian Lefebvre dHellencourt
Overview
Explore the profile of Christian Lefebvre dHellencourt including associated specialties, affiliations and a list of published articles.
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39
Citations
1070
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Recent Articles
1.
Clain J, Couret D, Bringart M, Meilhac O, Lefebvre dHellencourt C, Diotel N
IBRO Neurosci Rep
. 2025 Jan;
18():16-30.
PMID: 39816479
It is well recognized that type II Diabetes (T2D) and overweight/obesity are established risk factors for stroke, worsening also their consequences. However, the underlying mechanisms by which these disorders aggravate...
2.
Bhale A, Meilhac O, Lefebvre dHellencourt C, Vijayalakshmi M, Venkataraman K
Biofactors
. 2024 Apr;
50(5):922-956.
PMID: 38661230
High-density lipoproteins (HDLs) play a vital role in lipid metabolism and cardiovascular health, as they are intricately involved in cholesterol transport and inflammation modulation. The proteome of HDL particles is...
3.
Clain J, Couret D, Bringart M, Lecadieu A, Meilhac O, Lefebvre dHellencourt C, et al.
Eur J Neurosci
. 2024 Apr;
59(11):3009-3029.
PMID: 38576159
Metabolic disorders are risk factors for stroke exacerbating subsequent complications. Rapidly after brain injury, a glial scar forms, preventing excessive inflammation and limiting axonal regeneration. Despite the growing interest in...
4.
El Safadi D, Lebeau G, Turpin J, Lefebvre dHellencourt C, Diotel N, Viranaicken W, et al.
Viruses
. 2024 Jan;
16(1).
PMID: 38257725
Zika virus (ZIKV) is a pathogenic member of the flavivirus family, with several unique characteristics. Unlike any other arbovirus, ZIKV can be transmitted sexually and maternally, and thus produce congenital...
5.
Narra S, Gence L, Youssouf L, Couprie J, Giraud P, Diotel N, et al.
Zebrafish
. 2023 Aug;
20(5):200-209.
PMID: 37643300
Regenerative medicine is an emerging field of research aiming to understand the wound healing mechanisms and to develop new therapeutic strategies. Nanocarriers are used to improve drug bioavailability, solubility, and...
6.
McPherson C, Kelly-Rajan K, Lefebvre dHellencourt C, Harry G
Curr Protoc
. 2023 Jan;
3(1):e638.
PMID: 36622815
Microglia function as the tissue-specific resident macrophages of the nervous system, performing immune and non-immune functions. These functions are critical to development and to maintain homeostasis in the nervous system...
7.
Narra S, Rondeau P, Fernezelian D, Gence L, Ghaddar B, Bourdon E, et al.
J Comp Neurol
. 2022 Oct;
531(2):238-255.
PMID: 36282721
Microglia are macrophage-like cells exerting determinant roles in neuroinflammatory and oxidative stress processes during brain regeneration. We used zebrafish as a model of brain plasticity and repair. First, by performing...
8.
Clain J, Couret D, Planesse C, Krejbich-Trotot P, Meilhac O, Lefebvre dHellencourt C, et al.
Brain Sci
. 2022 May;
12(5).
PMID: 35625066
Adiponectin exhibits pleiotropic effects, including anti-inflammatory, anti-apoptotic, anti-oxidant, and neuroprotective ones. Although some studies have documented brain expression in different rodent models of its receptors, AdipoR1 and AdipoR2, their global...
9.
Ghaddar B, Bringart M, Lefebvre dHellencourt C, Meilhac O, Diotel N
Zebrafish
. 2021 May;
18(3):190-206.
PMID: 34028307
Overweight and obesity are worldwide epidemic health threats. They recently emerged as disruptors of brain homeostasis leading to a wide variety of neurologic disorders. This study aims at developing a...
10.
Dobi A, Rosanaly S, Devin A, Baret P, Meilhac O, Harry G, et al.
Microvasc Res
. 2020 Oct;
133:104098.
PMID: 33075405
During diabetes mellitus, advanced glycation end-products (AGEs) are major contributors to the development of alterations in cerebral capillaries, leading to the disruption of the blood-brain barrier (BBB). Consequently, this is...