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Christian Lacks Lino Cardenas

Explore the profile of Christian Lacks Lino Cardenas including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 370
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Recent Articles
1.
Alvarez K, Aguilar-Pineda J, Ortiz-Manrique M, Paredes-Calderon M, Cardenas-Quispe B, Vera-Lopez K, et al.
Front Mol Neurosci . 2023 Mar; 16:1104585. PMID: 36873109
Evidence suggests that there may be racial differences in risk factors associated with the development of Alzheimer's disease and related dementia (ADRD). We used whole-genome sequencing analysis and identified a...
2.
Lino Cardenas C, Briere L, Sweetser D, Lindsay M, Musolino P
J Clin Invest . 2023 Jan; 133(5). PMID: 36649075
No abstract available.
3.
Starr L, Lindsay M, Lino Cardenas C, Yetman A
Am J Med Genet A . 2022 Dec; 191(3):786-793. PMID: 36584339
Heterozygous missense variants in TGFBR1, encoding one subunit of the transforming growth factor-beta receptor, are a well-established cause of Loeys-Dietz syndrome (LDS)-an autosomal dominant disorder with variable phenotypic expression. Patients...
4.
Chou E, Chaffin M, Simonson B, Pirruccello J, Akkad A, Nekoui M, et al.
Arterioscler Thromb Vasc Biol . 2022 Sep; 42(11):1355-1374. PMID: 36172868
Background: Mural cells in ascending aortic aneurysms undergo phenotypic changes that promote extracellular matrix destruction and structural weakening. To explore this biology, we analyzed the transcriptional features of thoracic aortic...
5.
Zekavat S, Chou E, Zekavat M, Pampana A, Paruchuri K, Lino Cardenas C, et al.
JAMA Cardiol . 2022 Mar; 7(4):396-406. PMID: 35234813
Importance: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized nonatherosclerotic cause of acute myocardial infarction enriched among individuals with early-onset myocardial infarction but is of unclear etiology. Objective: To...
6.
Goyzueta-Mamani L, Barazorda-Ccahuana H, Chavez-Fumagalli M, Alvarez K, Aguilar-Pineda J, Vera-Lopez K, et al.
Molecules . 2022 Feb; 27(3). PMID: 35164183
Background: Despite research on the molecular bases of Alzheimer's disease (AD), effective therapies against its progression are still needed. Recent studies have shown direct links between AD progression and neurovascular...
7.
Gould R, Aziz H, Woods C, Seman-Senderos M, Sparks E, Preuss C, et al.
Nat Genet . 2018 Nov; 51(1):42-50. PMID: 30455415
Bicuspid aortic valve (BAV) is a common congenital heart defect (population incidence, 1-2%) that frequently presents with ascending aortic aneurysm (AscAA). BAV/AscAA shows autosomal dominant inheritance with incomplete penetrance and...
8.
Isselbacher E, Lino Cardenas C, Lindsay M
Circulation . 2016 Jun; 133(24):2516-28. PMID: 27297344
Thoracic aortic aneurysm is a potentially life-threatening condition in that it places patients at risk for aortic dissection or rupture. However, our modern understanding of the pathogenesis of thoracic aortic...
9.
Lino Cardenas C, Henaoui I, Courcot E, Roderburg C, Cauffiez C, Aubert S, et al.
PLoS Genet . 2013 Mar; 9(2):e1003291. PMID: 23459460
As miRNAs are associated with normal cellular processes, deregulation of miRNAs is thought to play a causative role in many complex diseases. Nevertheless, the precise contribution of miRNAs in fibrotic...
10.
Lino Cardenas C, Devos A, Toure A, Cardenas Garcia J, Kenani A, Migot-Nabias F, et al.
Mol Biol Rep . 2011 May; 39(2):1503-8. PMID: 21617944
The human Cytochrome P450 4A11 (CYP4A11) is a major ω-hydroxylase involved in the regulation of blood pressure in the kidney through the conversion of arachidonic acid into 20-hydroxyeicosatetraenoic acid (20-HETE)....