Christian D Lorenz
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Explore the profile of Christian D Lorenz including associated specialties, affiliations and a list of published articles.
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88
Citations
504
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Recent Articles
1.
Moller D, van der Walt M, Oosthuizen C, Serian M, Serem J, Lorenz C, et al.
ACS Omega
. 2025 Feb;
10(5):4699-4710.
PMID: 39959037
The rise in antimicrobial resistance has led to an increased desire to understand how antimicrobial peptides (AMPs) can be better engineered to kill antibiotic-resistant bacteria. Previously, we showed that C-terminal...
2.
Lopez-Rios de Castro R, Santana-Bonilla A, Ziolek R, Lorenz C
J Chem Inf Model
. 2025 Feb;
65(4):1679-1684.
PMID: 39929140
Molecular dynamics simulations have become essential tools in the study of soft matter and biological macromolecules. The large amount of high-dimensional data associated with such simulations does not straightforwardly elucidate...
3.
Ishkhanyan H, Santana-Bonilla A, Lorenz C
J Chem Inf Model
. 2025 Feb;
65(4):1694-1701.
PMID: 39928985
Accurately describing a nanoparticle's interface is crucial for understanding its internal structure, interfacial properties, and ultimately, its functionality. While current computational methods provide reasonable descriptions for spherical and quasi-spherical nanoparticles,...
4.
Hoose A, Garcia-Ruiz J, Blake C, Lally C, Briones A, Hoogenboom B, et al.
Langmuir
. 2025 Feb;
41(6):3757-3767.
PMID: 39919312
Antimicrobial resistance has motivated the search for antimicrobial agents with multimodal mechanisms of action. Host defense peptides and bacteriocins hold particular promise in this regard. Among many molecules discovered to...
5.
Van Wyk R, Serem J, Oosthuizen C, Semenya D, Serian M, Lorenz C, et al.
Biochemistry
. 2025 Jan;
64(4):841-859.
PMID: 39873636
C-terminal amidation of antimicrobial peptides (AMPs) is a frequent minor modification used to improve antibacterial potency, commonly ascribed to increased positive charge, protection from proteases, and a stabilized secondary structure....
6.
Jorgensen C, Linville R, Galea I, Lambden E, Vogele M, Chen C, et al.
J Chem Inf Model
. 2025 Jan;
65(3):1067-1084.
PMID: 39823383
Permeability is a measure of the degree to which cells can transport molecules across biological barriers. Units of permeability are distance per unit time (typically cm/s), where accurate measurements are...
7.
Li Y, Lorenz C, Holland G
Langmuir
. 2024 Oct;
40(43):22824-22834.
PMID: 39431416
Hydroxyapatite (HAP) exhibits a highly oriented hierarchical structure in biological hard tissues. The formation and selective crystalline orientation of HAP is a process that involves functional biomineralization proteins abundant in...
8.
Emergent conformational and aggregation properties of synergistic antimicrobial peptide combinations
Serian M, Mason A, Lorenz C
Nanoscale
. 2024 Oct;
16(44):20657-20669.
PMID: 39422704
Synergy between antimicrobial peptides (AMPs) may be the key to their evolutionary success and could be exploited to develop more potent antibacterial agents. One of the factors thought to be...
9.
Pettitt A, Shukla V, Figueiredo A, Newton L, McCarthy S, Tabor A, et al.
Biophys J
. 2024 Sep;
123(21):3798-3811.
PMID: 39340152
Intrinsically disordered proteins (IDPs) often contain proline residues that undergo cis/trans isomerization. While molecular dynamics (MD) simulations have the potential to fully characterize the proline cis and trans subensembles, they...
10.
Pabois O, Dong Y, Kampf N, Lorenz C, Doutch J, Avila-Sierra A, et al.
Commun Mater
. 2024 Sep;
5(1):158.
PMID: 39238825
Designing plant protein-based aqueous lubricants can be of great potential to achieve sustainability objectives by capitalising on inherent functional groups without using synthetic chemicals; however, such a concept remains in...