Christian Behrends
Overview
Explore the profile of Christian Behrends including associated specialties, affiliations and a list of published articles.
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Articles
102
Citations
10103
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Recent Articles
11.
Nalbach K, Schifferer M, Bhattacharya D, Ho-Xuan H, Tseng W, Williams L, et al.
Nat Commun
. 2023 Feb;
14(1):870.
PMID: 36797266
Hereditary sensory and autonomic neuropathy 9 (HSAN9) is a rare fatal neurological disease caused by mis- and nonsense mutations in the gene encoding for Tectonin β-propeller repeat containing protein 2...
12.
Sekar R, Motzler K, Kwon Y, Novikoff A, Julg J, Najafi B, et al.
Cell Metab
. 2022 Dec;
34(12):2047.
PMID: 36476936
No abstract available.
13.
Schmitt D, Bozkurt S, Henning-Domres P, Huesmann H, Eimer S, Bindila L, et al.
Autophagy
. 2022 Nov;
19(7):2146-2147.
PMID: 36416088
Autophagosome isolation enables the thorough investigation of structural components and engulfed materials. Recently, we introduced a novel antibody-based FACS-mediated method for isolation of native macroautophagic/autophagic vesicles and confirmed the quality...
14.
Jia J, Wang F, Bhujabal Z, Peters R, Mudd M, Duque T, et al.
Autophagy
. 2022 Nov;
19(6):1893-1895.
PMID: 36394332
The functions of mammalian Atg8 proteins (mATG8s) expand beyond canonical autophagy and include processes collectively referred to as Atg8ylation. Global modulation of protein synthesis under stress conditions is governed by...
15.
Sekar R, Motzler K, Kwon Y, Novikoff A, Julg J, Najafi B, et al.
Cell Metab
. 2022 Oct;
34(11):1824-1842.e9.
PMID: 36243006
During mammalian energy homeostasis, the glucagon receptor (Gcgr) plays a key role in regulating both glucose and lipid metabolisms. However, the mechanisms by which these distinct signaling arms are differentially...
16.
Schmitt D, Bozkurt S, Henning-Domres P, Huesmann H, Eimer S, Bindila L, et al.
EMBO Rep
. 2022 Oct;
23(12):e53065.
PMID: 36215690
Autophagy is responsible for clearance of an extensive portfolio of cargoes, which are sequestered into vesicles, called autophagosomes, and are delivered to lysosomes for degradation. The pathway is highly dynamic...
17.
Jia J, Wang F, Bhujabal Z, Peters R, Mudd M, Duque T, et al.
J Cell Biol
. 2022 Sep;
221(11).
PMID: 36179369
We report that lysosomal damage is a hitherto unknown inducer of stress granule (SG) formation and that the process termed membrane atg8ylation coordinates SG formation with mTOR inactivation during lysosomal...
18.
Siebert A, Gattringer V, Weishaupt J, Behrends C
Life Sci Alliance
. 2022 Sep;
5(12).
PMID: 36114006
The founding member of the F-box protein family, Cyclin-F, serves as a substrate adaptor for the E3 ligase Skp1-Cul1-F-box (SCF)<sup>Cyclin-F</sup> which is responsible for ubiquitination of proteins involved in cell...
19.
Guner G, Assfalg M, Zhao K, Dreyer T, Lahiri S, Lo Y, et al.
EMBO Mol Med
. 2022 Sep;
14(10):e16084.
PMID: 36069059
Fn14 is a cell surface receptor with key functions in tissue homeostasis and injury but is also linked to chronic diseases. Despite its physiological and medical importance, the regulation of...
20.
Zhou D, Borsa M, Puleston D, Zellner S, Capera J, Sanderson S, et al.
Nat Commun
. 2022 Sep;
13(1):5174.
PMID: 36055998
CD4+ T cells are pivotal cells playing roles in the orchestration of humoral and cytotoxic immune responses. It is known that CD4+ T cell proliferation relies on autophagy, but identification...