Chris W J van der Weijden
Overview
Explore the profile of Chris W J van der Weijden including associated specialties, affiliations and a list of published articles.
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17
Citations
163
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Recent Articles
1.
van der Hoorn A, Manusiwa L, van der Weide H, Sinnige P, Huitema R, Brouwer C, et al.
J Clin Med
. 2025 Jan;
14(2).
PMID: 39860562
Diffusion weighted imaging (DWI) is used for monitoring purposes for lower-grade glioma (LGG). While the apparent diffusion coefficient (ADC) is clinically used, various DWI models have been developed to better...
2.
van der Weijden C, Ahmed A, van der Hoorn A, Zhu J, Wu C, Wang Y, et al.
J Nucl Med
. 2024 Dec;
66(1):136-141.
PMID: 39638431
Multiple sclerosis (MS) is a neurodegenerative disease characterized by demyelinated lesions in the brain and spinal cord. A few clinical studies using PET to image myelin in the brain have...
3.
van der Weijden C, Pitombeira M, Peretti D, Campanholo K, Kolinger G, Rimkus C, et al.
J Clin Med
. 2024 Sep;
13(17).
PMID: 39274448
: Multiple sclerosis (MS) has two main phenotypes: relapse-remitting MS (RRMS) and progressive MS (PMS), distinguished by disability profiles and treatment response. Differentiating them using conventional MRI is challenging. :...
4.
Providencia L, van der Weijden C, Mohr P, van Sluis J, van Snick J, Slart R, et al.
J Nucl Med
. 2024 Mar;
65(4):600-606.
PMID: 38485272
Because of the limited axial field of view of conventional PET scanners, the internal carotid arteries are commonly used to obtain an image-derived input function (IDIF) in quantitative brain PET....
5.
Ghazanfari N, Doorduin J, van der Weijden C, Willemsen A, Glaudemans A, van Waarde A, et al.
Mol Imaging Biol
. 2024 Jan;
26(2):351-359.
PMID: 38263484
Purpose: Estrogen receptors (ER) are implicated in psychiatric disorders. We assessed if ER availability in the human brain could be quantified using 16α-[F]-fluoro-17β-estradiol ([F]FES) positron emission tomography (PET). Procedures: Seven...
6.
Mossel P, Arif W, Salvi de Souza G, Varela L, van der Weijden C, Boersma H, et al.
Eur J Nucl Med Mol Imaging
. 2023 Aug;
50(13):3917-3927.
PMID: 37552369
Introduction: P-glycoprotein (P-gp) is one of the most studied efflux transporters at the blood-brain barrier. It plays an important role in brain homeostasis by protecting the brain from a variety...
7.
van der Weijden C, Mossel P, Bartels A, Dierckx R, Luurtsema G, Lammertsma A, et al.
Eur J Nucl Med Mol Imaging
. 2023 Jan;
50(6):1636-1650.
PMID: 36651951
Pharmacokinetic modelling with arterial sampling is the gold standard for analysing dynamic PET data of the brain. However, the invasive character of arterial sampling prevents its widespread clinical application. Several...
8.
van der Weijden C, van der Hoorn A, Wang Y, Willemsen A, Dierckx R, Lammertsma A, et al.
Neuroimage
. 2022 Nov;
264:119772.
PMID: 36436711
Multiple sclerosis (MS) is an inflammatory demyelinating disease. Current treatments are focussed on immune suppression to modulate pathogenic activity that causes myelin damage. New treatment strategies are needed to prevent...
9.
van der Weijden C, Biondetti E, Gutmann I, Dijkstra H, McKerchar R, Faria D, et al.
Brain
. 2022 Nov;
146(4):1243-1266.
PMID: 36408715
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer with water between the wraps. The measurement of damage to the myelin sheaths, the evaluation of the...
10.
van der Weijden C, Meilof J, van der Hoorn A, Zhu J, Wu C, Wang Y, et al.
Eur J Nucl Med Mol Imaging
. 2022 Apr;
49(10):3492-3507.
PMID: 35366079
Purpose: Multiple sclerosis (MS) is a disease characterized by inflammatory demyelinated lesions. New treatment strategies are being developed to stimulate myelin repair. Quantitative myelin imaging could facilitate these developments. This...