Chris Thoburn
Overview
Explore the profile of Chris Thoburn including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
221
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0
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Recent Articles
1.
Alden S, Charmsaz S, Li H, Tsai H, Danilova L, Munjal K, et al.
J Immunother Cancer
. 2025 Jan;
13(1).
PMID: 39832896
Background: Obesity is a risk factor for developing cancer but is also associated with improved outcomes after treatment with immune checkpoint inhibitors (ICIs), a phenomenon called the obesity paradox. To...
2.
Baretti M, Danilova L, Durham J, Betts C, Cope L, Sidiropoulos D, et al.
Nat Commun
. 2024 Nov;
15(1):9801.
PMID: 39532835
Pancreatic ductal adenocarcinoma (PDA) is characterized by low cytotoxic lymphocytes, abundant immune-suppressive cells, and resistance to immune checkpoint inhibitors (ICI). Preclinical PDA models showed the HDAC inhibitor entinostat reduced myeloid...
3.
Kao C, Charmsaz S, Alden S, Brancati M, Li H, Balaji A, et al.
J Clin Invest
. 2024 Oct;
134(20).
PMID: 39403935
BACKGROUNDImmune-related adverse events (irAEs) and their associated morbidity/mortality are a key concern for patients receiving immune checkpoint inhibitors (ICIs). Prospective evaluation of the drivers of irAEs in a diverse pan-tumor...
4.
Robinson T, Prince G, Thoburn C, Warlick E, Ferguson A, Kasamon Y, et al.
Leuk Lymphoma
. 2018 Apr;
59(12):2801-2811.
PMID: 29616857
Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic stem cell malignancies. Currently, approved drugs are given with non-curative intent as the only known cure is allogeneic bone marrow...
5.
Joseph C, Darrah E, Shah A, Skora A, Casciola-Rosen L, Wigley F, et al.
Science
. 2013 Dec;
343(6167):152-7.
PMID: 24310608
Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. Scleroderma is an autoimmune connective tissue disease in which patients make antibodies to...
6.
Savage W, Savage J, Tobian A, Thoburn C, Hamilton R, Schroeder J, et al.
Transfusion
. 2011 Sep;
52(3):575-81.
PMID: 21883267
Background: The mechanisms that underlie allergic transfusion reactions (ATRs) are not well characterized, but likely involve recipient, donor, and product factors. To assess product factors associated with ATRs, we investigated...
7.
Savage W, Barber J, Mukhina G, Hu R, Chen G, Matsui W, et al.
Exp Hematol
. 2008 Nov;
37(1):42-51.
PMID: 19013003
Objective: Investigate the contribution of PIG-A mutations to clonal expansion in paroxysmal nocturnal hemoglobinuria (PNH). Materials And Methods: Primary CD34+ hematopoietic progenitors from PNH patients were assayed for annexin-V positivity...