Chris Seebregts
Overview
Explore the profile of Chris Seebregts including associated specialties, affiliations and a list of published articles.
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12
Citations
573
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0
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Recent Articles
1.
Heekes A, Tiffin N, Dane P, Mutemaringa T, Smith M, Zinyakatira N, et al.
BMJ Glob Health
. 2018 May;
3(Suppl 2):e000565.
PMID: 29713507
Information systems designed to support health promotion in pregnancy, such as the MomConnect programme, are potential sources of clinical information which can be used to identify pregnancies prospectively and early...
2.
Cassol E, Rossouw T, Malfeld S, Mahasha P, Slavik T, Seebregts C, et al.
BMC Infect Dis
. 2015 Oct;
15:430.
PMID: 26475133
Background: Intestinal macrophages are key regulators of inflammatory responses to the gut microbiome and play a central role in maintaining tissue homeostasis and epithelial integrity. However, little is known about...
3.
Cassol E, Malfeld S, Mahasha P, Bond R, Slavik T, Seebregts C, et al.
J Infect Dis
. 2013 Jun;
208(7):1113-22.
PMID: 23749968
Background: Human immunodeficiency virus type 1 (HIV-1) infection is associated with a massive depletion of intestinal CD4(+) T cells that is only partially reversed by combination antiretroviral therapy (cART). Here,...
4.
Murrell B, de Oliveira T, Seebregts C, Kosakovsky Pond S, Scheffler K
PLoS Comput Biol
. 2012 May;
8(5):e1002507.
PMID: 22589711
The evolution of substitutions conferring drug resistance to HIV-1 is both episodic, occurring when patients are on antiretroviral therapy, and strongly directional, with site-specific resistant residues increasing in frequency over...
5.
Huang K, Goedhals D, Carlson J, Brockman M, Mishra S, Brumme Z, et al.
PLoS One
. 2011 May;
6(4):e19018.
PMID: 21544209
We lack the understanding of why HIV-infected individuals in South Africa progress to AIDS. We hypothesised that in end-stage disease there is a shifting dynamic between T cell imposed immunity...
6.
Cassol E, Rossouw T, Seebregts C, Cassol S
J Infect Dis
. 2011 Feb;
203(5):747-8.
PMID: 21278212
No abstract available.
7.
Cassol E, Malfeld S, Mahasha P, van der Merwe S, Cassol S, Seebregts C, et al.
J Infect Dis
. 2010 Jul;
202(5):723-33.
PMID: 20629534
Background: Microbial translocation contributes to immune activation and disease progression during chronic human immunodeficiency virus type 1 (HIV-1) infection. However, its role in the African AIDS epidemic remains controversial. Here,...
8.
Huang K, Goedhals D, Fryer H, van Vuuren C, Katzourakis A, de Oliveira T, et al.
Antivir Ther
. 2009 Nov;
14(7):975-84.
PMID: 19918101
Background: We aimed to characterize the molecular epidemiology of HIV type-1 (HIV-1) and the prevalence of drug-associated mutations prior to initiating highly active antiretroviral therapy (HAART) in the Free State...
9.
Allen C, Jazayeri D, Miranda J, Biondich P, Mamlin B, Wolfe B, et al.
Stud Health Technol Inform
. 2007 Oct;
129(Pt 1):382-6.
PMID: 17911744
The challenge of scaling up HIV treatment in Africa has led to a new emphasis on improving health systems in impoverished areas. One aspect of this is the development and...
10.
Jaspan H, Flisher A, Myer L, Mathews C, Seebregts C, Berwick J, et al.
J Adolesc
. 2006 Dec;
30(2):353-9.
PMID: 17187853
Reporting bias in adolescent behavioural research may be overcome with the use of personal digital assistants (PDA) or other computer based technologies. However, there is little insight into the use...