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Chris Proudfoot

Explore the profile of Chris Proudfoot including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 750
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Recent Articles
1.
Cousens C, Meehan J, Collie D, Wright S, Chang Z, Todd H, et al.
Genes (Basel) . 2024 Aug; 15(8). PMID: 39202379
Ovine pulmonary adenocarcinoma (OPA) is an infectious, neoplastic lung disease of sheep that causes significant animal welfare and economic issues throughout the world. Understanding OPA pathogenesis is key to developing...
2.
Eaton S, Murdoch F, Rzechorzek N, Thompson G, Hartley C, Blacklock B, et al.
Cells . 2022 Sep; 11(17). PMID: 36078049
The impact of neurological disorders is recognised globally, with one in six people affected in their lifetime and few treatments to slow or halt disease progression. This is due in...
3.
Nelvagal H, Eaton S, Wang S, Eultgen E, Takahashi K, Le S, et al.
J Clin Invest . 2022 Aug; 132(20). PMID: 36040802
CLN1 disease, also called infantile neuronal ceroid lipofuscinosis (NCL) or infantile Batten disease, is a fatal neurodegenerative lysosomal storage disorder resulting from mutations in the CLN1 gene encoding the soluble...
4.
Proudfoot C, Burkard C
Emerg Top Life Sci . 2021 Feb; 1(2):209-219. PMID: 33525766
One of the major burdens on the livestock industry is loss of animals and decrease in production efficiency due to disease. Advances in sequencing technology and genome-editing techniques provide the...
5.
McCleary S, Strong R, McCarthy R, Edwards J, Howes E, Stevens L, et al.
Sci Rep . 2020 Jun; 10(1):8951. PMID: 32488046
African swine fever virus (ASFV) causes a lethal, haemorrhagic disease in domestic swine that threatens pig production across the globe. Unlike domestic pigs, warthogs, which are wildlife hosts of the...
6.
Proudfoot C, Lillico S, Tait-Burkard C
Anim Front . 2020 Feb; 9(3):6-12. PMID: 32002257
No abstract available.
7.
He Z, Proudfoot C, Whitelaw C, Lillico S
Springerplus . 2016 Jul; 5(1):814. PMID: 27390654
Background: Genome editors such as CRISPR/Cas9 and TALENs are at the forefront of research into methodologies for targeted modification of the mammalian genome. To date few comparative studies have been...
8.
Lillico S, Proudfoot C, King T, Tan W, Zhang L, Mardjuki R, et al.
Sci Rep . 2016 Feb; 6:21645. PMID: 26898342
We describe a fundamentally novel feat of animal genetic engineering: the precise and efficient substitution of an agronomic haplotype into a domesticated species. Zinc finger nuclease in-embryo editing of the...
9.
Whitelaw C, Joshi A, Kumar S, Lillico S, Proudfoot C
J Dairy Res . 2016 Feb; 83(1):3-11. PMID: 26869106
It has been thirty years since the first genetically engineered animal with altered milk composition was reported. During the intervening years, the world population has increased from 5bn to 7bn...
10.
Tan W, Proudfoot C, Lillico S, Whitelaw C
Transgenic Res . 2016 Feb; 25(3):273-87. PMID: 26847670
One of the most powerful strategies to investigate biology we have as scientists, is the ability to transfer genetic material in a controlled and deliberate manner between organisms. When applied...