Chris Orr
Overview
Explore the profile of Chris Orr including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
44
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kato H, Salgado M, Mendez D, Gonzalez N, Rawson J, Ligot D, et al.
Sci Rep
. 2024 May;
14(1):12402.
PMID: 38811610
Evaluating the quality of isolated human islets before transplantation is crucial for predicting the success in treating Type 1 diabetes. The current gold standard involves time-intensive in vivo transplantation into...
2.
Cobb J, Rawson J, Gonzalez N, Orr C, Kandeel F, Husseiny M
PLoS One
. 2024 May;
19(5):e0303863.
PMID: 38781241
Type 1 diabetes (T1D)-associated hyperglycemia develops, in part, from loss of insulin-secreting beta cells. The degree of glycemic dysregulation and the age at onset of disease can serve as indicators...
3.
Kato H, Chen H, Shang K, Izumi K, Koba N, Tsuchiya T, et al.
Cell Transplant
. 2024 May;
33:9636897241249556.
PMID: 38742734
Pancreatic islet transplantation is one of the clinical options for certain types of diabetes. However, difficulty in maintaining islets prior to transplantation limits the clinical expansion of islet transplantations. Our...
4.
Gonzalez N, Kato H, Tixi W, Ortiz J, Orr C, Shih H, et al.
Cell Transplant
. 2023 Jun;
32:9636897231182497.
PMID: 37345228
"Firefly rats" ubiquitously express the luciferase reporter gene under the control of constitutively active promoter in inbred Lewis rats. Due to the minimal immunogenicity of luciferase, wide applications of Firefly...
5.
Cobb J, Soliman S, Retuerto M, Quijano J, Orr C, Ghannoum M, et al.
PLoS One
. 2023 May;
18(5):e0285905.
PMID: 37224176
We developed an oral Salmonella-based vaccine that prevents and reverses diabetes in non-obese diabetic (NOD) mice. Related to this, the gastrointestinal tract harbors a complex dynamic population of microorganisms, the...
6.
Komatsu H, Qi M, Gonzalez N, Salgado M, Medrano L, Rawson J, et al.
Cell Transplant
. 2021 Oct;
30:9636897211052291.
PMID: 34628956
Prior to transplantation into individuals with type 1 diabetes, in vitro assays are used to evaluate the quality, function and survival of isolated human islets. In addition to the assessments...
7.
Oancea A, Omori K, Orr C, Rawson J, Dafoe D, Al-Abdullah I, et al.
Islets
. 2020 Jan;
12(1):9-19.
PMID: 31935153
The pancreas of brain-dead donors is the primary source of islets for transplantation. However, brain death mediates systemic inflammation, which may affect the quantity and quality of isolated islets. Our...
8.
Orr C, Stratton J, Rao I, Al-Sayed M, Smith C, El-Shahawy M, et al.
Cell Transplant
. 2015 Apr;
25(1):83-95.
PMID: 25853639
A mathematical nonlinear regression model of several parameters (baseline insulin intake, posttransplant 2-h postprandial blood glucose, and stimulated C-peptide) from type 1 diabetics with HbA1c <6.5% who do not require...
9.
Walmsley D, Milne J, Kay L, Orr C, Pacey L
Br Dent J
. 2014 May;
216(10):546-7.
PMID: 24852969
No abstract available.
10.
Todorov I, Nair I, Avakian-Mansoorian A, Rawson J, Omori K, Ito T, et al.
Transplantation
. 2010 Aug;
90(8):836-42.
PMID: 20697327
Background: Assays for assessing human islet cell quality, which provide results before transplantation, would be beneficial to improve the outcomes for islet transplantation therapy. Parameters such as percent β-cell apoptosis...