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Chris M Rands

Explore the profile of Chris M Rands including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 295
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Recent Articles
1.
Rossitto M, Dejardin S, Rands C, Le Gras S, Migale R, Rafiee M, et al.
Nat Commun . 2022 Jul; 13(1):4412. PMID: 35906245
Gonadal sexual fate in mammals is determined during embryonic development and must be actively maintained in adulthood. In the mouse ovary, oestrogen receptors and FOXL2 protect ovarian granulosa cells from...
2.
Ademi H, Djari C, Mayere C, Neirijnck Y, Sararols P, Rands C, et al.
Cell Rep . 2022 Jun; 39(11):110935. PMID: 35705036
Leydig cells (LCs) are the major androgen-producing cells in the testis. They arise from steroidogenic progenitors (SPs), whose origins, maintenance, and differentiation dynamics remain largely unknown. Single-cell transcriptomics reveal that...
3.
Mayere C, Neirijnck Y, Sararols P, Rands C, Stevant I, Kuhne F, et al.
FASEB J . 2021 Mar; 35(4):e21452. PMID: 33749946
Despite the importance of germ cell (GC) differentiation for sexual reproduction, the gene networks underlying their fate remain unclear. Here, we comprehensively characterize the gene expression dynamics during sex determination...
4.
Starikova E, Tikhonova P, Prianichnikov N, Rands C, Zdobnov E, Ilina E, et al.
Bioinformatics . 2020 Apr; 36(12):3882-3884. PMID: 32311023
Summary: Phigaro is a standalone command-line application that is able to detect prophage regions taking raw genome and metagenome assemblies as an input. It also produces dynamic annotated 'prophage genome...
5.
Rands C, Brussow H, Zdobnov E
Environ Microbiol . 2019 Jul; 21(11):3989-4001. PMID: 31314945
Negativicutes are gram-negative bacteria characterized by two cell membranes, but they are phylogenetically a side-branch of gram-positive Firmicutes that contain only a single membrane. We asked whether viruses (phages) infecting...
6.
Rands C, Starikova E, Brussow H, Kriventseva E, Govorun V, Zdobnov E
Environ Microbiol . 2018 Jul; 20(6):2288-2300. PMID: 30014616
Antibiotic resistance is increasing among pathogens, and the human microbiome contains a reservoir of antibiotic resistance genes. Acidaminococcus intestini is the first Negativicute bacterium (Gram-negative Firmicute) shown to be resistant...
7.
Li C, Zhang Y, Li J, Kong L, Hu H, Pan H, et al.
Gigascience . 2015 Feb; 3(1):27. PMID: 25671092
Background: Penguins are flightless aquatic birds widely distributed in the Southern Hemisphere. The distinctive morphological and physiological features of penguins allow them to live an aquatic life, and some of...
8.
Rands C, Meader S, Ponting C, Lunter G
PLoS Genet . 2014 Jul; 10(7):e1004525. PMID: 25057982
Ten years on from the finishing of the human reference genome sequence, it remains unclear what fraction of the human genome confers function, where this sequence resides, and how much...
9.
Rands C, Darling A, Fujita M, Kong L, Webster M, Clabaut C, et al.
BMC Genomics . 2013 Feb; 14:95. PMID: 23402223
Background: A classical example of repeated speciation coupled with ecological diversification is the evolution of 14 closely related species of Darwin's (Galápagos) finches (Thraupidae, Passeriformes). Their adaptive radiation in the...