Chris J Howard
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Explore the profile of Chris J Howard including associated specialties, affiliations and a list of published articles.
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24
Citations
378
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Recent Articles
11.
Abbott J, Palmer G, Howard C, Hope J, Brown W
Infect Immun
. 2004 Nov;
72(12):7360-6.
PMID: 15557669
Organisms in the genus Anaplasma express an immunodominant major surface protein 2 (MSP2), composed of a central hypervariable region (HVR) flanked by highly conserved regions. Throughout Anaplasma marginale infection, recombination...
12.
Werling D, Hope J, Howard C, Jungi T
Immunology
. 2003 Dec;
111(1):41-52.
PMID: 14678198
Toll-like receptors (TLR) have been described as partially sharing signalling pathways but showing unique ligand specificity and tissue distribution. Here, the response of bovine macrophages (Mphi) and dendritic cells (DC),...
13.
Hope J, Whelan A, Hewinson R, Vordermeier M, Howard C
Vet Immunol Immunopathol
. 2003 Sep;
95(1-2):21-31.
PMID: 12969633
The response of DC, and the subsequent stimulation of T cells, is an essential part of the initiation of immune responses following microbial challenge. The response of human DC to...
14.
Stephens S, Brownlie J, Charleston B, Howard C
Immunology
. 2003 Aug;
110(1):48-57.
PMID: 12941140
Two phenotypically distinct subpopulations of dendritic cells (SIRPalpha+ CC81Ag- DC and SIRPalpha- CC81Ag+ DC) have previously been identified in bovine afferent lymph which show functional differences when assayed in vitro....
15.
Zhang Y, Palmer G, Abbott J, Howard C, Hope J, Brown W
Vaccine
. 2003 Jun;
21(23):3307-18.
PMID: 12804862
Immunostimulatory oligodeoxynucleotides containing unmethylated CpG dinucleotides (CpG ODN) stimulate IL-12-dependent Th1 dominated cytokine and enhanced IgG responses when co-delivered with antigen to mice. However, the CpG ODN sequences that are...
16.
Bajer A, Garcia-Tapia D, Jordan K, Haas K, Werling D, Howard C, et al.
J Leukoc Biol
. 2003 Jan;
73(1):100-6.
PMID: 12525567
Regulation of humoral responses involves multiple cell types including the requirements for cognate interactions between T and B cells to drive CD40-dependent responses to T-dependent antigens. A third cell type...
17.
Haig D, Thomson J, McInnes C, Deane D, Anderson I, McCaughan C, et al.
Virus Res
. 2002 Nov;
90(1-2):303-16.
PMID: 12457984
Orf virus causes pustular skin lesions (orf) in sheep, goats and humans. The virus encodes an interleukin-10 (orfvIL-10) that is identical in amino acid composition to ovine IL-10 (ovIL-10) over...
18.
Mwangi W, Brown W, Lewin H, Howard C, Hope J, Baszler T, et al.
J Immunol
. 2002 Sep;
169(7):3837-46.
PMID: 12244180
DNA-based immunization is a contemporary strategy for developing vaccines to prevent infectious diseases in animals and humans. Translating the efficacy of DNA immunization demonstrated in murine models to the animal...
19.
Werling D, Collins R, Taylor G, Howard C
J Leukoc Biol
. 2002 Aug;
72(2):297-304.
PMID: 12149420
We compared the effects of live or inactivated bovine respiratory syncytial virus (BRSV) on cytokine production by bovine monocyte-derived dendritic cells (MoDC). We also investigated the response of resting memory...
20.
Gliddon D, Howard C
Eur J Immunol
. 2002 May;
32(5):1472-81.
PMID: 11981836
Two major sub-populations of dendritic cells (DC) are present in afferent lymph draining the skin of cattle distinguished by expression of signal regulator protein alpha (SIRPalpha). The SIRPalpha(-) population expresses...