Chris Brightling
Overview
Explore the profile of Chris Brightling including associated specialties, affiliations and a list of published articles.
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Articles
62
Citations
1679
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Recent Articles
1.
Kuks P, Kole T, Kraft M, Siddiqui S, Fabbri L, Rabe K, et al.
ERJ Open Res
. 2025 Feb;
11(1).
PMID: 39963164
Introduction: Neutrophilic asthma has been suggested to be a clinically distinct phenotype characterised by more severe airflow obstruction and higher exacerbation risk. However, this has only been assessed in few...
2.
El-Husseini Z, Karp T, Lan A, Gillett T, Qi C, Khalenkow D, et al.
Am J Respir Cell Mol Biol
. 2025 Jan;
PMID: 39836087
Asthma is a genetically complex inflammatory airway disease associated with over 200 Single nucleotide polymorphisms (SNPs). However, the functional effects of many asthma-associated SNPs in lung and airway epithelial samples...
3.
Gharibzadeh S, Routen A, Razieh C, Zaccardi F, Lawson C, Gillies C, et al.
EClinicalMedicine
. 2025 Jan;
79:103005.
PMID: 39834716
Background: People with diabetes are at increased risk of hospitalisation, morbidity, and mortality following SARS-CoV-2 infection. Long-term outcomes for people with diabetes previously hospitalised with COVID-19 are, however, unknown. This...
4.
Khaleva E, Brightling C, Eiwegger T, Altraja A, Begin P, Blumchen K, et al.
Eur Respir J
. 2024 Nov;
PMID: 39510551
Background: We have previously developed Core Outcome Measures sets for Severe Asthma (COMSA) by multi-stakeholder consensus. There are no patient-centred tools to quantify response to biologics for severe asthma. We...
5.
Kermani N, Chung K, Macis G, Santini G, Clemeno F, Versi A, et al.
Eur Respir J
. 2024 Oct;
64(5).
PMID: 39401856
Background: Lung quantitative computed tomography (qCT) severe asthma clusters have been reported, but their replication and underlying disease mechanisms are unknown. We identified and replicated qCT clusters of severe asthma...
6.
7.
Karp T, Faiz A, van Nijnatten J, Kerstjens H, Boudewijn I, Kraft M, et al.
Thorax
. 2024 Jul;
79(10):905-914.
PMID: 39009441
Introduction: Asthma is an inflammatory airways disease encompassing multiple phenotypes and endotypes. Several studies suggested gene expression in nasal epithelium to serve as a proxy for bronchial epithelium, being a...
8.
Tan R, Murphy A, Brightling C, Shaw D
NPJ Prim Care Respir Med
. 2024 Jun;
34(1):16.
PMID: 38937520
The British Thoracic Society (BTS) and Scottish Intercollege Guidelines Network (SIGN), as well as National Institute for Health and Care Excellence (NICE), have previously produced separate asthma guidance differing in...
9.
Kole T, Muiser S, Kraft M, Siddiqui S, Fabbri L, Rabe K, et al.
BMJ Open Respir Res
. 2024 Jun;
11(1).
PMID: 38901877
Background: Asthma is a heterogeneous disease with a prevalence and severity that differs between male and female patients. Question: What are differences between male and female patients with asthma with...
10.
Lawson C, Moss A, Arnold J, Bagot C, Banerjee A, Berry C, et al.
Open Heart
. 2024 May;
11(1.
PMID: 38802280
Background: Pre-existing cardiovascular disease (CVD) or cardiovascular risk factors have been associated with an increased risk of complications following hospitalisation with COVID-19, but their impact on the rate of recovery...