Dave Singh
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Explore the profile of Dave Singh including associated specialties, affiliations and a list of published articles.
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492
Citations
13632
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Recent Articles
1.
Criner G, Singh D, Papi A, Jison M, Makulova N, Shih V, et al.
Ther Adv Respir Dis
. 2025 Mar;
19:17534666241312060.
PMID: 40072041
Summary● This is a plain language summary of two articles originally published in and . These articles presented the results of GALATHEA and TERRANOVA, two clinical studies that took place...
2.
Bate S, Fortescue R, Fullwood C, Sperrin M, Simmonds M, Fally M, et al.
BMJ Open
. 2025 Mar;
15(3):e095541.
PMID: 40044194
Introduction: Inhaled corticosteroids (ICS) can improve clinical outcomes in patients with chronic obstructive pulmonary disease (COPD) and eosinophilic airway inflammation, but they also increase the risk of side effects like...
3.
Gale C, Hurst J, Hawkins N, Bourbeau J, Han M, Lam C, et al.
Eur J Prev Cardiol
. 2025 Mar;
PMID: 40037333
Background: Cardiovascular disease is a common comorbidity in chronic obstructive pulmonary disease (COPD). Yet cardiovascular disease and risk is under diagnosed in COPD and is often undertreated, increasing the risk...
4.
Vogelmeier C, Rabe K, Bhatt S, Hanania N, Bafadhel M, Christenson S, et al.
Respir Med
. 2025 Mar;
:108015.
PMID: 40024335
Background: The body mass index, airflow obstruction, dyspnea, and exercise capacity (BODE) index predicts 5-year mortality risk in chronic obstructive pulmonary disease (COPD); higher scores predict worse outcomes. Dupilumab, a...
5.
Kuks P, Kole T, Kraft M, Siddiqui S, Fabbri L, Rabe K, et al.
ERJ Open Res
. 2025 Feb;
11(1).
PMID: 39963164
Introduction: Neutrophilic asthma has been suggested to be a clinically distinct phenotype characterised by more severe airflow obstruction and higher exacerbation risk. However, this has only been assessed in few...
6.
Caponetti G, Sala F, Cervetti A, Colombo D, Tiberio E, Singh D
Pharmacol Res Perspect
. 2025 Feb;
13(1):e70064.
PMID: 39918069
The aim of this study was to evaluate safety, tolerability, and pharmacokinetics (PK) of single and multiple doses of a novel inhaled formulation of voriconazole (ZP-059). In the single ascending...
7.
Bhatt S, Rabe K, Hanania N, Vogelmeier C, Bafadhel M, Christenson S, et al.
Lancet Respir Med
. 2025 Feb;
13(3):234-243.
PMID: 39900091
Background: Dupilumab, a fully human monoclonal antibody, blocks the shared receptor component for IL-4 and IL-13, which are key drivers of type 2 inflammation. We aimed to characterise the efficacy...
8.
Bhatt S, Rabe K, Hanania N, Vogelmeier C, Bafadhel M, Christenson S, et al.
Chest
. 2025 Feb;
PMID: 39894389
Background: Patient-reported outcomes should be considered alongside clinical assessments to guide therapy for COPD. Research Question: Does add-on dupilumab treatment improve health-related quality of life and respiratory symptoms in patients...
9.
Higham A, Booth S, Dungwa J, Singh D
Pulmonology
. 2025 Jan;
31(1):2430032.
PMID: 39883495
Age-related lung function decline is associated with small airway closure and gas trapping. The mechanisms which cause these changes are not fully understood. It has been suggested that COPD is...
10.
El-Husseini Z, Karp T, Lan A, Gillett T, Qi C, Khalenkow D, et al.
Am J Respir Cell Mol Biol
. 2025 Jan;
PMID: 39836087
Asthma is a genetically complex inflammatory airway disease associated with over 200 Single nucleotide polymorphisms (SNPs). However, the functional effects of many asthma-associated SNPs in lung and airway epithelial samples...