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Chow Yin Wong

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Recent Articles
11.
Sim Y, Ng G, Ng C, Rajasegaran V, Wong S, Liu W, et al.
BMC Med Genomics . 2019 Oct; 12(1):142. PMID: 31647027
Background: Known collectively as breast fibroepithelial lesions (FELs), the common fibroadenomas (FAs) and the rarer phyllodes tumors (PTs) are a heterogenous group of biphasic neoplasms. Owing to limited tissue availability,...
12.
Nasir N, Ng C, Rajasegaran V, Wong S, Liu W, Ng G, et al.
J Pathol . 2019 Aug; 249(4):447-460. PMID: 31411343
Fibroepithelial lesions (FELs) are a heterogeneous group of tumours comprising fibroadenomas (FAs) and phyllodes tumours (PTs). Here we used a 16-gene panel that was previously discovered to be implicated in...
13.
Kang S, Guan J, Tan H, Chu T, Thike A, Bernado C, et al.
Clin Cancer Res . 2018 Dec; 25(8):2588-2600. PMID: 30593516
Purpose: Trastuzumab-based chemotherapy has shown remarkable clinical benefits for patients with HER2-positive breast cancer. However, treatment regimens involving trastuzumab had little or no effect for a subset of patients. Preliminary...
14.
Ng Y, Tan V, Pek W, Chang J, Sim Y, Ong K, et al.
Breast Cancer . 2018 Sep; 26(2):165-171. PMID: 30218304
Background: Nipple-sparing mastectomy (NSM) allows for excellent postmastectomy reconstruction aesthetics and is used for both therapeutic and risk-reducing purposes. Reservations regarding the potential for locoregional recurrence and concerns about nipple-areolar...
15.
Sim Y, Tan V, Sidek N, Chia D, Tan B, Madhukumar P, et al.
ANZ J Surg . 2018 Aug; 88(10):982-987. PMID: 30141242
Background: Women with unilateral breast cancer have an increased risk of developing bilateral breast cancer (BBC). Patients with metachronous BBC (mBBC) usually have an earlier age of onset, and their...
16.
Chan C, Munusamy P, Loke S, Koh G, Yang A, Law H, et al.
Oncotarget . 2018 Mar; 9(16):12796-12804. PMID: 29560110
Genome-wide association studies (GWAS) have proven highly successful in identifying single nucleotide polymorphisms (SNPs) associated with breast cancer (BC) risk. The majority of these studies are on European populations, with...
17.
Ooi W, Xing M, Xu C, Yao X, Ramlee M, Lim M, et al.
Nat Commun . 2016 Sep; 7:12983. PMID: 27677335
Regulatory enhancer elements in solid tumours remain poorly characterized. Here we apply micro-scale chromatin profiling to survey the distal enhancer landscape of primary gastric adenocarcinoma (GC), a leading cause of...
18.
Ng Y, Tan V, Goh T, Yong W, Wong C, Ho G, et al.
Breast J . 2016 Sep; 23(1):59-66. PMID: 27633549
Post-mastectomy breast reconstruction is an integral component of breast cancer treatment. It is often perceived that women in Asian countries have a lower rate of post-mastectomy reconstruction than Western populations....
19.
Lee C, Tan V, Tan B, Madhukumar P, Yong W, Wong C, et al.
Ann Acad Med Singap . 2016 Jul; 45(6):261-3. PMID: 27412061
No abstract available.
20.
Sin E, Wong C, Yong W, Ong K, Madhukumar P, Tan V, et al.
J Clin Pathol . 2015 Dec; 69(4):364-9. PMID: 26670744
Malignant transformation of the epithelial component of phyllodes tumours (PT) is rare and only reported in literature as sporadic cases of carcinoma associated with PTs. We report the clinicopathological characteristics...