Choon Leng So
Overview
Explore the profile of Choon Leng So including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
92
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0
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Recent Articles
1.
Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells
So C, Robitaille M, Sadras F, McCullough M, Milevskiy M, Goodhill G, et al.
Commun Biol
. 2024 Apr;
7(1):467.
PMID: 38632473
Differences in shape can be a distinguishing feature between different cell types, but the shape of a cell can also be dynamic. Changes in cell shape are critical when cancer...
2.
So C, Robitaille M, Monteith G
Cell Calcium
. 2022 Dec;
109:102685.
PMID: 36493538
No abstract available.
3.
Bong A, Hua T, So C, Peters A, Robitaille M, Tan Y, et al.
Cancers (Basel)
. 2022 Oct;
14(19).
PMID: 36230716
Although breast cancer cells often exhibit both abnormal AKT signaling and calcium signaling, the association between these two pathways is unclear. Using a combination of pharmacological tools, siRNA and CRISPR/Cas9...
4.
Robitaille M, Chan S, Peters A, Dai L, So C, Bong A, et al.
Int J Mol Sci
. 2022 Jun;
23(11).
PMID: 35682546
A remodeling of calcium homeostasis, including calcium influx via store-operated calcium entry (SOCE), is a feature of breast cancers. SOCE is critical to maintain calcium balance in the endoplasmic reticulum...
5.
So C, Meinert C, Xia Q, Robitaille M, Roberts-Thomson S, Monteith G
Cell Calcium
. 2022 Mar;
104:102569.
PMID: 35248793
Both matrix stiffening and remodeling of calcium signaling occur in breast cancers, with downstream consequences linked to the progression of the disease. However, the potential intersection between calcium signaling and...
6.
Azimi I, Robitaille M, Armitage K, So C, Milevskiy M, Northwood K, et al.
Int J Mol Sci
. 2020 Dec;
21(24).
PMID: 33322037
Epithelial to mesenchymal transition (EMT) in cancer is important in therapeutic resistance and invasiveness. Calcium signaling is key to the induction of EMT in breast cancer cells. Although inhibition of...
7.
So C, Milevskiy M, Monteith G
Lab Invest
. 2019 Dec;
100(2):199-206.
PMID: 31822791
Transient receptor potential cation channel subfamily V (TRPV) channels play important roles in a variety of cellular processes. One example includes the sensory role of TRPV1 that is sensitive to...
8.
So C, Saunus J, Roberts-Thomson S, Monteith G
Semin Cell Dev Biol
. 2018 Nov;
94:74-83.
PMID: 30439562
The past two decades have seen the identification of important roles for calcium signalling in many of the hallmarks of cancer. One of the cancer types that has been a...
9.
Ngai M, So C, Sullivan M, Ho H, Chai C
ChemMedChem
. 2015 Nov;
11(1):72-80.
PMID: 26593399
3-Substituted indolin-2-ones are an important class of compounds that display a wide range of biological activities. Sunitinib is an orally available multiple tyrosine kinase inhibitor that has been approved by...