Ching-I A Wang
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Explore the profile of Ching-I A Wang including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
475
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Recent Articles
1.
Brust A, Wang C, Daly N, Kennerly J, Sadeghi M, Christie M, et al.
Angew Chem Int Ed Engl
. 2018 Apr;
57(19):5203.
PMID: 29701320
No abstract available.
2.
Gori A, Wang C, Harvey P, Rosengren K, Bhola R, Gelmi M, et al.
Angew Chem Int Ed Engl
. 2014 Dec;
54(4):1361-4.
PMID: 25483297
The design of disulfide bond mimetics is an important strategy for optimising cysteine-rich peptides in drug development. Mimetics of the drug lead conotoxin MrIA, in which one disulfide bond is...
3.
Brust A, Wang C, Daly N, Kennerley J, Sadeghi M, Christie M, et al.
Angew Chem Int Ed Engl
. 2013 Oct;
52(46):12020-3.
PMID: 24115503
No abstract available.
4.
Wang C, Shaikh N, Ramu S, Lewis R
Mol Pharmacol
. 2012 Aug;
82(5):898-909.
PMID: 22874414
The human norepinephrine transporter (NET) is implicated in many neurological disorders and is a target of tricyclic antidepressants and nisoxetine (NX). We used molecular docking simulations to guide the identification...
5.
Grishin A, Wang C, Muttenthaler M, Alewood P, Lewis R, Adams D
J Biol Chem
. 2010 May;
285(29):22254-63.
PMID: 20466726
Non-native disulfide isomers of alpha-conotoxins are generally inactive although some unexpectedly demonstrate comparable or enhanced bioactivity. The actions of "globular" and "ribbon" isomers of alpha-conotoxin AuIB have been characterized on...
6.
Muttenthaler M, Nevin S, Grishin A, Ngo S, Choy P, Daly N, et al.
J Am Chem Soc
. 2010 Feb;
132(10):3514-22.
PMID: 20163143
Alpha-conotoxins are tightly folded miniproteins that antagonize nicotinic acetylcholine receptors (nAChR) with high specificity for diverse subtypes. Here we report the use of selenocysteine in a supported phase method to...
7.
Jin A, Daly N, Nevin S, Wang C, Dutertre S, Lewis R, et al.
J Med Chem
. 2008 Aug;
51(18):5575-84.
PMID: 18754612
Alpha-conotoxins are competitive antagonists of nicotinic acetylcholine receptors (nAChRs). The majority of currently characterized alpha-conotoxins have a 4/7 loop size, and the major features of neuronal alpha-conotoxins include a globular...
8.
Wang C, Guncar G, Forwood J, Teh T, Catanzariti A, Lawrence G, et al.
Plant Cell
. 2007 Sep;
19(9):2898-912.
PMID: 17873095
The gene-for-gene mechanism of plant disease resistance involves direct or indirect recognition of pathogen avirulence (Avr) proteins by plant resistance (R) proteins. Flax rust (Melampsora lini) AvrL567 avirulence proteins and...
9.
Schmidt S, Williams S, Wang C, Sornaraj P, James B, Kobe B, et al.
Plant J
. 2007 Apr;
50(6):1107-17.
PMID: 17461785
The M flax-rust resistance (R) gene is predicted to encode a 150-kDa protein of the Toll-interleukin-like receptor-nucleotide binding site-leucine rich repeat (TIR-NBS-LRR) class of plant disease resistance proteins and provides...
10.
Guncar G, Wang C, Forwood J, Teh T, Catanzariti A, Ellis J, et al.
Acta Crystallogr Sect F Struct Biol Cryst Commun
. 2007 Mar;
63(Pt 3):209-13.
PMID: 17329816
Metal-binding sites are ubiquitous in proteins and can be readily utilized for phasing. It is shown that a protein crystal structure can be solved using single-wavelength anomalous diffraction based on...