Chimeddulam Dalaijamts
Overview
Explore the profile of Chimeddulam Dalaijamts including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
138
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lee R, Tao Z, Prybutok S, Jang S, Dalaijamts C, Chiu W, et al.
Clim Risk Manag
. 2024 Feb;
41.
PMID: 38298905
As extreme weather events have become more frequently observed in recent decades, concerns about exposure to potential flood risk have increased, especially in underserved and socially vulnerable communities. Galena Park,...
2.
Dalaijamts C, Cichocki J, Luo Y, Rusyn I, Chiu W
Toxicol Sci
. 2021 May;
182(2):168-182.
PMID: 33988684
Quantification of interindividual variability is a continuing challenge in risk assessment, particularly for compounds with complex metabolism and multi-organ toxicity. Toxicokinetic variability for perchloroethylene (perc) was previously characterized across 3...
3.
Dalaijamts C, Cichocki J, Luo Y, Rusyn I, Chiu W
Toxicol Appl Pharmacol
. 2020 May;
400:115069.
PMID: 32445755
Background: Nonalcoholic fatty liver disease (NAFLD), a major cause of chronic liver disease in the Western countries with increasing prevalence worldwide, may substantially affect chemical toxicokinetics and thereby modulate chemical...
4.
Sakolish C, Chen Z, Dalaijamts C, Mitra K, Liu Y, Fulton T, et al.
Toxicol In Vitro
. 2019 Dec;
63:104752.
PMID: 31857146
Kidney is a major route of xenobiotic excretion, but the accuracy of preclinical data for predicting in vivo clearance is limited by species differences and non-physiologic 2D culture conditions. Microphysiological...
5.
Wang M, Orr A, He S, Dalaijamts C, Chiu W, Tamamis P, et al.
ACS Omega
. 2019 Nov;
4(18):17702-17713.
PMID: 31681876
Among the numerous contaminants of soil, glyphosate and paraquat are two of the most widely used herbicides that are commonly detected in the environment. Soil and sediment contaminated with glyphosate,...
6.
Stermer A, Klein D, Wilson S, Dalaijamts C, Bai C, Hall S, et al.
Environ Toxicol Pharmacol
. 2019 Mar;
68:1-3.
PMID: 30836291
Trichloroethylene (TCE) is a persistent environmental contaminant that causes male reproductive toxicity. We investigated whether transient increases in TCE exposure modulated male reproductive toxicity by exposing rats via daily oral...
7.
Blanchette A, Grimm F, Dalaijamts C, Hsieh N, Ferguson K, Luo Y, et al.
Clin Pharmacol Ther
. 2018 Oct;
105(5):1175-1186.
PMID: 30346629
"Thorough QT/corrected QT (QTc)" (TQT) studies are cornerstones of clinical cardiovascular safety assessment. However, TQT studies are resource intensive, and preclinical models predictive of the threshold of regulatory concern are...
8.
Grimm F, Blanchette A, House J, Ferguson K, Hsieh N, Dalaijamts C, et al.
ALTEX
. 2018 Jul;
35(4):441-452.
PMID: 29999168
Assessing inter-individual variability in responses to xenobiotics remains a substantial challenge, both in drug development with respect to pharmaceuticals and in public health with respect to environmental chemicals. Although approaches...
9.
Chiu W, Axelrad D, Dalaijamts C, Dockins C, Shao K, Shapiro A, et al.
Environ Health Perspect
. 2018 Jul;
126(6):067009.
PMID: 29968566
Background: The National Academies recommended risk assessments redefine the traditional noncancer Reference Dose (RfD) as a probabilistically derived risk-specific dose, a framework for which was recently developed by the World...
10.
Dalaijamts C, Cichocki J, Luo Y, Rusyn I, Chiu W
Toxicol Appl Pharmacol
. 2018 Jun;
352:142-152.
PMID: 29857080
Background: Perchloroethylene (perc) induced target organ toxicity has been associated with tissue-specific metabolic pathways. Previous physiologically-based pharmacokinetic (PBPK) modeling of perc accurately predicted oxidative metabolites but suggested the need to...