Chien-Yu Chen
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Explore the profile of Chien-Yu Chen including associated specialties, affiliations and a list of published articles.
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Articles
197
Citations
2444
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Recent Articles
1.
Luo Z, Chen C, Li S
Small Methods
. 2025 Mar;
:e2401860.
PMID: 40059474
Recent advances in the development of tumor-targeting nanoparticles (NPs) significantly enhance cancer therapies by effectively increasing the therapeutic window of drugs, improving the response of tumor cells, and augmenting anti-tumor...
2.
Li P, Sun Y, Juan H, Chen C, Tsai H, Huang J
Brief Bioinform
. 2025 Feb;
26(1).
PMID: 39998433
With the exponential growth of biomedical literature, leveraging Large Language Models (LLMs) for automated medical knowledge understanding has become increasingly critical for advancing precision medicine. However, current approaches face significant...
3.
Wei B, Cheng-Hong Tsai X, Sun K, Lo M, Hung S, Chou W, et al.
NPJ Precis Oncol
. 2025 Feb;
9(1):35.
PMID: 39900774
The rapid development of deep learning has revolutionized medical image processing, including analyzing whole slide images (WSIs). Despite the demonstrated potential for characterizing gene mutations directly from WSIs in certain...
4.
Wang M, Chen C, Lin Y, Liu Y, Liu Y, Li W, et al.
J Clin Med
. 2025 Jan;
14(2.
PMID: 39860660
Pancreaticoduodenectomy (PD) is a major surgery associated with significant morbidity and mortality, especially in older adult patients. Malnutrition is a common complication in these patients and is linked to poorer...
5.
Yen T, Hsu C, Lee N, Wu C, Wang H, Lee K, et al.
J Microbiol Immunol Infect
. 2024 Dec;
58(1):86-93.
PMID: 39643526
Background: Severe community-acquired pneumonia was associated with high morbidity and mortality in children. However, species-level microbiome of lower airway was sparse, and we used shotgun metagenomic next-generation sequencing to explore...
6.
Chen C, Chou T, Chuang C, Chien W, Huang B
Opt Express
. 2024 Nov;
32(14):24715-24727.
PMID: 39538904
In computer-generated holography, spatial light modulators are predominantly used for image reconstruction. However, the quality of the reconstructed images is often compromised by laser speckle and zero-order light diffraction. To...
7.
Chi D, Lewis F, Weinstein P, Mancl L, Milgrom P, Edwards T, et al.
Contemp Clin Trials
. 2024 Nov;
147:107734.
PMID: 39489399
Background: This study protocol describes a community-based intervention that will seek to reduce added sugar intake in Yup'ik Alaska Native children by targeting reductions in sugar-sweetened fruit drinks. Methods: A...
8.
Hung T, Liu W, Lai S, Chuang H, Lee Y, Lin H, et al.
Genome Res
. 2024 Sep;
34(8):1211-1223.
PMID: 39251346
The killer-cell immunoglobulin-like receptor (KIR) gene complex, a highly polymorphic region of the human genome that encodes proteins involved in immune responses, poses strong challenges in genotyping owing to its...
9.
Chang C, Dai S, Chen C, Huang L, Chen Y, Hsu J
Pestic Biochem Physiol
. 2024 Jul;
203:106001.
PMID: 39084797
Diamondback moth (DBM, Plutella xylostella) is the most significant pest of cruciferous vegetables as they rapidly develop high-level resistance to many insecticides. Monitoring DBM susceptibility and target-site mutation frequency is...
10.
Chuang T, Chou H, Kuan C, Liu S, Kao C, Wu Y, et al.
Front Endocrinol (Lausanne)
. 2024 Jun;
15:1415865.
PMID: 38894739
Objectives: To explore the correlation between mitochondrial quantity and the blastocyst development timeline as well as their respective contributions to early pregnancy. Methods: A retrospective study was conducted using a...