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Chien-Te K Tseng

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Articles 69
Citations 4166
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Recent Articles
1.
Octaviani C, Huang P, Bi-Hung P, Gray G, Tseng C
Sci Rep . 2025 Mar; 15(1):8797. PMID: 40087358
The current outbreak of highly pathogenic avian influenza (HPAI) viruses of the H5N1 subtype clade 2.3.4.4b in dairy cattle in the United States has affected nearly 900 dairy farms and...
2.
Liao Y, Ma H, Wang Z, Wang S, He Y, Chang Y, et al.
Proc Natl Acad Sci U S A . 2025 Feb; 122(6):e2406659122. PMID: 39908098
The rapid evolution of the viral genome has led to the continual generation of new variants of SARS-CoV-2. Developing antibody drugs with broad-spectrum and high efficiency is a long-term task....
3.
Saenkham-Huntsinger P, Drelich A, Huang P, Peng B, Tseng C
J Gen Virol . 2024 Oct; 105(10). PMID: 39475775
Up to one-third of individuals suffering from acute SARS-CoV-2 infection with the onset of severe-to-mild diseases could develop several symptoms of neurological disorders, which could last long after resolving the...
4.
Hsu J, Saenkham-Huntsinger P, Huang P, Octaviani C, Drelich A, Peng B, et al.
Front Microbiol . 2024 Oct; 15:1455462. PMID: 39380676
COVID-19 presents with a plethora of neurological signs and symptoms despite being characterized as a respiratory disease, including seizures, anxiety, depression, amnesia, attention deficits, and alterations in consciousness. The olfactory...
5.
Drelich A, Rayavara K, Hsu J, Saenkham-Huntsinger P, Judy B, Tat V, et al.
PLoS Pathog . 2024 Jun; 20(6):e1011777. PMID: 38913740
COVID-associated coagulopathy seemly plays a key role in post-acute sequelae of SARS- CoV-2 infection. However, the underlying pathophysiological mechanisms are poorly understood, largely due to the lack of suitable animal...
6.
Westberg M, Su Y, Zou X, Huang P, Rustagi A, Garhyan J, et al.
Sci Transl Med . 2024 Mar; 16(738):eadi0979. PMID: 38478629
Inhibitors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (M) such as nirmatrelvir (NTV) and ensitrelvir (ETV) have proven effective in reducing the severity of COVID-19, but...
7.
Carter B, Huang P, Liu G, Liang Y, Lin P, Peng B, et al.
Front Immunol . 2023 Mar; 14:1135815. PMID: 36969239
Licensed COVID-19 vaccines ameliorate viral infection by inducing production of neutralizing antibodies that bind the SARS-CoV-2 Spike protein and inhibit viral cellular entry. However, the clinical effectiveness of these vaccines...
8.
Du L, Kou Z, Ma C, Tao X, Wang L, Zhao G, et al.
PLoS One . 2022 Dec; 17(12):e0278474. PMID: 36469521
[This corrects the article DOI: 10.1371/journal.pone.0081587.].
9.
Zhu J, Jain S, Sha J, Batra H, Ananthaswamy N, Kilgore P, et al.
mBio . 2022 Jul; 13(4):e0182222. PMID: 35900097
The U.S. Food and Drug Administration-authorized mRNA- and adenovirus-based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in preventing COVID-19, but they do not induce efficient mucosal immunity...
10.
Zhu J, Li L, Drelich A, Chenna B, Mellott D, Taylor Z, et al.
Front Chem . 2022 Jul; 10:867928. PMID: 35860632
Cysteine proteases comprise an important class of drug targets, especially for infectious diseases such as Chagas disease (cruzain) and COVID-19 (3CL protease, cathepsin L). Peptide aldehydes have proven to be...