Chien-Chi Lin
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Explore the profile of Chien-Chi Lin including associated specialties, affiliations and a list of published articles.
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84
Citations
2341
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Recent Articles
1.
Nguyen H, Luong N, Peil J, Tong Y, Mitchell D, Fishel M, et al.
Biomacromolecules
. 2025 Jan;
26(2):1098-1110.
PMID: 39841789
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a dense extracellular matrix (ECM) exhibiting high stiffness and fast stress relaxation. In this work, gelatin-based viscoelastic hydrogels were developed to mimic the...
2.
Chang C, Lin C
Chembiochem
. 2025 Jan;
26(6):e202400955.
PMID: 39794304
Pancreatic ductal adenocarcinoma (PDAC) is marked by significant desmoplastic reactions, or the accumulation of excessive extracellular matrices. PDAC stroma has abnormally high stiffness, which alters cancer cell behaviors and creates...
3.
Arkenberg M, Jafarkhani M, Lin C, Hashino E
Stem Cell Reports
. 2025 Jan;
20(2):102386.
PMID: 39793574
The mechanical properties in the inner ear microenvironment play a key role in its patterning during embryonic development. To recapitulate inner ear development in vitro, three-dimensional tissue engineering strategies including...
4.
Duong V, Nguyen H, Luong N, Chang C, Lin C
Adv Funct Mater
. 2024 Nov;
34(36).
PMID: 39525288
Decellularized small intestine submucosa (dSIS) is a promising biomaterial for promoting tissue regeneration. Isolated from the submucosal layer of animal jejunum, SIS is rich in extracellular matrix (ECM) proteins, including...
5.
Duong V, Dang T, Le V, Le T, Nguyen C, Phan H, et al.
Biomaterials
. 2024 Sep;
314:122840.
PMID: 39321685
Skeletal muscle is composed of multiple fascicles, which are parallel bundles of muscle fibers surrounded by connective tissues that contain blood vessels and nerves. Here, we fabricated multifascicle human skeletal...
6.
Chang C, Nguyen H, Frahm E, Kolaczyk K, Lin C
RSC Appl Polym
. 2024 Jul;
2(4):656-669.
PMID: 39035826
Microgels are spherical hydrogels with physicochemical properties ideal for many biomedical applications. For example, microgels can be used as individual carriers for suspension cell culture or jammed/annealed into granular hydrogels...
7.
Khine Y, Nguyen H, Afolabi F, Lin C
Biomater Adv
. 2024 Mar;
159:213829.
PMID: 38531258
The mechanics of the tumor microenvironment (TME) significantly impact disease progression and the efficacy of anti-cancer therapeutics. While it is recognized that advanced in vitro cancer models will benefit cancer...
8.
Dimmitt N, Lin C
Macromolecules
. 2024 Mar;
57(4):1556-1568.
PMID: 38435678
The inverse electron demand Diels-Alder (iEDDA) reactions are highly efficient click chemistry increasingly utilized in bioconjugation, live cell labeling, and the synthesis and modification of biomaterials. iEDDA click reactions have...
9.
Xiong X, Huo Q, Li K, Cui C, Chang C, Park C, et al.
Theranostics
. 2024 Feb;
14(4):1430-1449.
PMID: 38389836
Osteosarcoma (OS), a common malignant bone tumor, calls for the investigation of novel treatment strategies. Low-intensity vibration (LIV) presents itself as a promising option, given its potential to enhance bone...
10.
Nguyen H, Lin C
Acta Biomater
. 2024 Feb;
177:203-215.
PMID: 38354874
The tumor microenvironment (TME) in pancreatic adenocarcinoma (PDAC) is a complex milieu of cellular and non-cellular components. Pancreatic cancer cells (PCC) and cancer-associated fibroblasts (CAF) are two major cell types...