Chiara Costabile
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Explore the profile of Chiara Costabile including associated specialties, affiliations and a list of published articles.
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25
Citations
131
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Recent Articles
1.
Galdi G, Costabile C
Chemistry
. 2024 Sep;
30(70):e202402774.
PMID: 39282892
Mechanistic studies on 1,2-oxyarylation of ethylene promoted by gold catalysts bearing hemilabile N-Heterocyclic Carbene (NHC^X) ligands were conducted by DFT calculations, exploring the whole catalytic cycle. After highest energy transition...
2.
Araszczuk A, Pierri G, Schettini R, Costabile C, Sala G, Di Marino L, et al.
Chemistry
. 2024 May;
30(36):e202400904.
PMID: 38699895
Two new chiral 1,2,3-triazole-containing macrocyclic oligoamides (i. e.: triazolopeptoid 4 and 5) were obtained through solid-phase synthesis of linear precursors followed by high dilution macrocyclization reaction. Theoretical (DFT) and spectroscopic...
3.
Sirignano M, DAmato A, Costabile C, Mariconda A, Crispini A, Scarpelli F, et al.
Front Chem
. 2023 Dec;
11:1260726.
PMID: 38124702
Imines are valuable key compounds for synthesizing several nitrogen-containing molecules used in biological and industrial fields. They have been obtained, as highly regioselective Markovnikov products, by reacting several alkynes with...
4.
Iacopetta D, Costabile C, La Chimia M, Mariconda A, Ceramella J, Scumaci D, et al.
ACS Med Chem Lett
. 2023 Nov;
14(11):1567-1575.
PMID: 37974945
-Heterocyclic carbene (NHC) metal complexes are attracting scientists' interest as an alluring class of metallodrugs. Indeed, the versatile functionalization of NHC ligands makes them optimal scaffolds to be developed in...
5.
DAmato A, Jiang L, Sala G, Kirshenbaum K, Costabile C, Furlan C, et al.
J Org Chem
. 2023 May;
88(11):6588-6598.
PMID: 37155983
Cyclic peptoids are macrocyclic oligomers of N-substituted glycines with specific folding abilities and excellent metal binding properties. In this work, we show how strategic positioning of chiral ()- and ()-(1-carboxyethyl)glycine...
6.
Araszczuk A, DAmato A, Schettini R, Costabile C, Sala G, Pierri G, et al.
Org Lett
. 2022 Oct;
24(42):7752-7756.
PMID: 36223077
Head-to-tail cyclization of linear oligoamides containing 4-benzylaminomethyl-1-1,2,3-triazol-1-yl acetic acid monomers afforded a novel class of "extended macrocyclic peptoids". The identification of the conformation in solution for a cyclodimer and the...
7.
Mariconda A, Iacopetta D, Sirignano M, Ceramella J, Costabile C, Pellegrino M, et al.
ChemMedChem
. 2022 Jul;
17(18):e202200345.
PMID: 35904129
In recent years, the number of people suffering from cancer has risen rapidly and the World Health Organization and U.S. and European governments have identified this pathology as a priority...
8.
Schettini R, DAmato A, Araszczuk A, Sala G, Costabile C, DUrsi A, et al.
Org Biomol Chem
. 2021 Aug;
19(34):7420-7431.
PMID: 34397051
A variety of cyclen and hexacyclen derivatives decorated with (S)-1-phenylethyl side chains or (S)-pyrrolidine units have been prepared via a reductive approach from the corresponding cyclic peptoids containing N-(S)-(1-phenylethyl)glycine and...
9.
DAmato A, Ghosh P, Costabile C, Sala G, Izzo I, Maayan G, et al.
Dalton Trans
. 2020 Apr;
49(18):6020-6029.
PMID: 32319496
A practical synthesis of preorganized tripodal enterobactin/corynebactin-type ligands (consisting of a C-symmetric macrocyclic peptoid core, three catecholamide coordinating units, and C, C, and C spacers) is reported. The formation of...
10.
DAmato A, Pierri G, Tedesco C, Sala G, Izzo I, Costabile C, et al.
J Org Chem
. 2019 Jul;
84(17):10911-10928.
PMID: 31339718
Controlling the network of intramolecular interactions encoded by α-chiral side chains and the equilibria between cis- and trans-amide junctions in cyclic peptoid architectures constitutes a significant challenge for the construction...