Chia Yi Liu
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Explore the profile of Chia Yi Liu including associated specialties, affiliations and a list of published articles.
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4
Citations
233
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Recent Articles
1.
Shin E, Huynh V, Neja S, Liu C, Raju A, Tan K, et al.
Sci Adv
. 2021 Mar;
7(12).
PMID: 33731348
What covalent modifications control the temporal ubiquitination of ERα and hence the duration of its transcriptional activity remain poorly understood. We show that GREB1, an ERα-inducible enzyme, catalyzes O-GlcNAcylation of...
2.
Khattar E, Kumar P, Liu C, Akincilar S, Raju A, Lakshmanan M, et al.
J Clin Invest
. 2016 Sep;
126(10):4045-4060.
PMID: 27643433
Transcriptional reactivation of telomerase reverse transcriptase (TERT) reconstitutes telomerase activity in the majority of human cancers. Here, we found that ectopic TERT expression increases cell proliferation, while acute reductions in...
3.
Koh C, Khattar E, Leow S, Liu C, Muller J, Ang W, et al.
J Clin Invest
. 2015 Apr;
125(5):2109-22.
PMID: 25893605
Constitutively active MYC and reactivated telomerase often coexist in cancers. While reactivation of telomerase is thought to be essential for replicative immortality, MYC, in conjunction with cofactors, confers several growth...
4.
Akincilar S, Low K, Liu C, Yan T, Oji A, Ikawa M, et al.
FEBS Lett
. 2015 Mar;
589(9):974-84.
PMID: 25749370
Besides its canonical function of catalyzing the formation of telomeric repeats, many groups have recently reported non-canonical functions of hTERT in particular, and telomerase in general. Regulating transcription is the...