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Chia-Hung Dylan Tsai

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Recent Articles
11.
Tsai C, Takayama T, Shimozyo Y, Akai T, Kaneko M
Biomicrofluidics . 2018 Jul; 12(3):034114. PMID: 29983839
An interesting phenomenon that vortices are sequentially generated on a microfluidic chip is investigated in this paper. The direction of every two adjacent vortices is opposite to each other, like...
12.
Lim J, Choi A, Kim H, Yoon H, Park S, Tsai C, et al.
ACS Appl Mater Interfaces . 2018 Apr; 10(17):14331-14341. PMID: 29649358
Cell migration is crucial in physiological and pathological processes such as embryonic development and wound healing; such migration is strongly guided by the surrounding nanostructured extracellular matrix. Previous studies have...
13.
Higashino N, Takayama T, Ito H, Horade M, Yamaguchi Y, Tsai C, et al.
Sensors (Basel) . 2018 Jan; 18(1). PMID: 29324699
In cell culture, the pH of the culture medium is one of the most important conditions. However, the culture medium may have non-uniform pH distribution due to activities of cells...
14.
Ito H, Murakami R, Sakuma S, Tsai C, Gutsmann T, Brandenburg K, et al.
Sci Rep . 2017 Feb; 7:43134. PMID: 28233788
Large deformability of erythrocytes in microvasculature is a prerequisite to realize smooth circulation. We develop a novel tool for the three-step "Catch-Load-Launch" manipulation of a human erythrocyte based on an...
15.
Tsai C, Kaneko M
Biomicrofluidics . 2016 Apr; 10(2):024116. PMID: 27076864
A vision-based on-chip sensor for sensing local pressure inside a microfluidic device is proposed and evaluated in this paper. The local pressure is determined from the change of color intensity...
16.
Murakami R, Tsai C, Kaneko M, Sakuma S, Arai F
Lab Chip . 2015 Jul; 15(16):3307-13. PMID: 26179936
An unexpected phenomenon of red blood cells bouncing back and forth between the walls inside a microfluidic channel was observed during experiments, and is presented as "Cell Pinball" in this...
17.
Monzawa T, Kaneko M, Tsai C, Sakuma S, Arai F
Biomicrofluidics . 2015 Feb; 9(1):014114. PMID: 25713696
An on-chip actuation transmitter for achieving fast and accurate cell manipulation is proposed. Instead of manipulating cell position by a directly connected macro-scale pump, polydimethylsiloxane deformation is used as a...
18.
Tsai C, Sakuma S, Arai F, Kaneko M
IEEE Trans Biomed Eng . 2014 Mar; 61(4):1187-95. PMID: 24658243
This paper proposes a new index for evaluating the stiffness-based deformability of a cell using a microchannel. In conventional approaches, the transit time of a cell through a microchannel is...
19.
Sakuma S, Kuroda K, Tsai C, Fukui W, Arai F, Kaneko M
Lab Chip . 2014 Jan; 14(6):1135-41. PMID: 24463842
Red blood cells (RBC) circulate the human body several hundred thousand times in their life span. Therefore, their deformability is really important, especially when they pass through a local capillary...
20.
Tsai C, Kaneko M, Sakuma S, Arai F
Annu Int Conf IEEE Eng Med Biol Soc . 2013 Oct; 2013:5525-8. PMID: 24110988
The effect of osmotic condition on a living cell inside a micro-channel is firstly studied in this work. By utilizing a high-speed camera, we observed distinct patterns of cell motion...