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Chia-Cheng Hung

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Recent Articles
1.
Lin P, Chiang Y, Tsai C, Chu C, Hung C, Su Y, et al.
Clin Exp Otorhinolaryngol . 2025 Feb; PMID: 39948052
Objective: Current state-run newborn hearing screening (NBHS) programs have limitations in identifying children with mild or late-onset sensorineural hearing impairment (SNHI). As more than 50% of pediatric SNHI cases are...
2.
Shen C, Afraj S, Hung C, Barve B, Kuo L, Lin Z, et al.
Bioorg Med Chem Lett . 2021 Mar; 41:127976. PMID: 33766765
A series of 1,4-naphthoquinone derivatives of lawsone (1), 6-hydroxy-1,4-naphthoquinone (2), and juglone (3) were synthesized by alkylation, acylation, and sulfonylation reactions. The yields of lawsone derivatives 1a-1k (type A), 6-hydroxy-1,4-naphthoquinone...
3.
Yu C, Lin T, Jou S, Lin C, Lin K, Lu M, et al.
Sci Rep . 2020 Jul; 10(1):11501. PMID: 32661308
Aneuploidy occurs within a significant proportion of childhood B-cell acute lymphoblastic leukemia (B-ALL). Some copy number variations (CNV), associated with novel subtypes of childhood B-ALL, have prognostic significance. A total...
4.
Yu C, Chang W, Jou S, Lin T, Chang Y, Lin C, et al.
Cancer Sci . 2019 Nov; 111(1):229-238. PMID: 31729120
TP53 alterations are frequent relapse-acquired mutations in childhood acute lymphoblastic leukemia (ALL). The present study evaluated the clinical significance of relapsed childhood ALL in Taiwan. Diagnostic and/or relapsed bone marrow...
5.
Hung C, Lee C, Wang Y, Chen C, Lin T, Su Y, et al.
Sci Rep . 2019 Oct; 9(1):15456. PMID: 31664061
Fragile X syndrome (FXS) is the most frequent genetic cause of intellectual disability (ID). It was previously believed that the FXS prevalence was low in Chinese population, and the cost-efficiency...
6.
Lu C, Tsao P, Ke Y, Lin Y, Lin Y, Hung C, et al.
J Pediatr . 2018 Apr; 199:144-150.e1. PMID: 29681450
Objective: To evaluate the feasibility and potential benefits of incorporating genetic and cytomegalovirus (CMV) screenings into the current newborn hearing screening (NHS) programs. Study Design: Newborns were recruited prospectively from...
7.
Wu C, Tsai C, Hung C, Lin Y, Lin Y, Huang F, et al.
Genet Med . 2016 Jun; 19(1):6-12. PMID: 27308839
Purpose: The feasibility of genetic screening for deafness-causing mutations in newborns has been reported in several studies. The aim of this study was to investigate the long-term results in those...
8.
Liang W, Chou P, Hung C, Su Y, Kan T, Chen W, et al.
J Neurol Sci . 2016 Mar; 362:304-8. PMID: 26944168
Limb-girdle muscular dystrophy type 2D (LGMD2D), an autosomal-recessive inherited LGMD, is caused by the mutations in SGCA. SGCA encodes alpha-sarcoglycan (SG) that forms a heterotetramer with other SGs in the...
9.
Yang C, Liau J, Huang W, Chang Y, Chang M, Lee J, et al.
Am J Transl Res . 2015 Dec; 7(10):2072-81. PMID: 26692951
Leiomyosarcoma is an aggressive soft tissue sarcoma with poor patient survival. The genetic changes of leiomyosarcoma remain to be discovered. In this study, we analyzed the genetic changes of 44...
10.
Huang C, Chang L, Tsai Y, Hung C, Fang M, Su Y, et al.
J Formos Med Assoc . 2013 Oct; 112(9):537-44. PMID: 24079714
Background/purpose: Patients with chromosomal translocation are highly vulnerable to produce unbalanced gametes that result in recurrent miscarriages, affected offspring, or infertility. Preimplantation genetic diagnosis (PGD) with blastomere biopsy and fluorescent...