Chi-Lee C Ho
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Explore the profile of Chi-Lee C Ho including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
82
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Recent Articles
1.
Ho C, Gilbert M, Urtecho G, Lee H, Drew D, Klempner S, et al.
Cancer Prev Res (Phila)
. 2024 Apr;
17(8):361-376.
PMID: 38669694
There is a high unmet need for early detection approaches for diffuse gastric cancer (DGC). We examined whether the stool proteome of mouse models of gastric cancer (GC) and individuals...
2.
Martchenko Shilman M, Bartolo G, Alameh S, Peterson J, Lawrence W, Peel J, et al.
ACS Infect Dis
. 2021 Jul;
7(8):2176-2191.
PMID: 34218660
Anthrax is caused by and can result in nearly 100% mortality due in part to anthrax toxin. Antimalarial amodiaquine (AQ) acts as a host-oriented inhibitor of anthrax toxin endocytosis. Here,...
3.
Hartmann S, Nusbaum D, Kim K, Alameh S, Ho C, Cruz R, et al.
ACS Infect Dis
. 2018 Oct;
4(12):1746-1754.
PMID: 30354048
Inflammasomes activate caspase-1 in response to molecular signals from pathogens and other dangerous stimuli as a part of the innate immune response. A previous study discovered a small-molecule, 4-fluoro- N'-[1-(2-pyridinyl)ethylidene]benzohydrazide,...
4.
Hartmann S, Lopez Cruz R, Alameh S, Ho C, Rabideau A, Pentelute B, et al.
ACS Infect Dis
. 2018 May;
4(8):1235-1245.
PMID: 29749721
Exploiting the host endocytic trafficking pathway is a common mechanism by which bacterial exotoxins gain entry to exert virulent effects upon the host cells. A previous study identified a small-molecule,...
5.
Zilbermintz L, Leonardi W, Jeong S, Sjodt M, McComb R, Ho C, et al.
Sci Rep
. 2015 Aug;
5:13476.
PMID: 26310922
A longstanding and still-increasing threat to the effective treatment of infectious diseases is resistance to antimicrobial countermeasures. Potentially, the targeting of host proteins and pathways essential for the detrimental effects...
6.
Jung M, Chamberlain B, Ho C, Gillespie E, Bradley K
ACS Med Chem Lett
. 2014 Jun;
5(4):363-7.
PMID: 24900841
EGA, 1, prevents the entry of multiple viruses and bacterial toxins into mammalian cells by inhibiting vesicular trafficking. The cellular target of 1 is unknown, and a structure-activity relationship study...
7.
Gillespie E, Ho C, Balaji K, Clemens D, Deng G, Wang Y, et al.
Proc Natl Acad Sci U S A
. 2013 Nov;
110(50):E4904-12.
PMID: 24191014
Pathogenic microorganisms and toxins have evolved a variety of mechanisms to gain access to the host-cell cytosol and thereby exert virulent effects upon the host. One common mechanism of cellular...