Cheryl L Smith
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Explore the profile of Cheryl L Smith including associated specialties, affiliations and a list of published articles.
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20
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1267
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Recent Articles
1.
Wong K, Cheng Y, Wu V, Kiseleva A, Li J, Poleshko A, et al.
Sci Adv
. 2024 Mar;
10(11):eadm9518.
PMID: 38478612
Extracellular signals are transmitted through kinase cascades to modulate gene expression, but it remains unclear how epigenetic changes regulate this response. Here, we provide evidence that growth factor-stimulated changes in...
2.
Kiseleva A, Cheng Y, Smith C, Katz R, Poleshko A
Nucleus
. 2023 Jan;
14(1):2165602.
PMID: 36633363
The eukaryotic genome is organized in three dimensions within the nucleus. Transcriptionally active chromatin is spatially separated from silent heterochromatin, a large fraction of which is located at the nuclear...
3.
Linares-Saldana R, Kim W, Bolar N, Zhang H, Koch-Bojalad B, Yoon S, et al.
Nat Genet
. 2021 Nov;
53(12):1723.
PMID: 34725478
No abstract available.
4.
Linares-Saldana R, Kim W, Bolar N, Zhang H, Koch-Bojalad B, Yoon S, et al.
Nat Genet
. 2021 Oct;
53(10):1480-1492.
PMID: 34611363
Higher-order chromatin structure regulates gene expression, and mutations in proteins mediating genome folding underlie developmental disorders known as cohesinopathies. However, the relationship between three-dimensional genome organization and embryonic development remains...
5.
Smith C, Lan Y, Jain R, Epstein J, Poleshko A
Sci Adv
. 2021 Sep;
7(39):eabj3035.
PMID: 34559565
The nuclear architecture of rod photoreceptor cells in nocturnal mammals is unlike that of other animal cells. Murine rod cells have an “inverted” chromatin organization with euchromatin at the nuclear...
6.
Smith C, Poleshko A, Epstein J
Nucleic Acids Res
. 2021 May;
49(11):6181-6195.
PMID: 34023908
Nuclear architecture influences gene regulation and cell identity by controlling the three-dimensional organization of genes and their distal regulatory sequences, which may be far apart in linear space. The genome...
7.
See K, Kiseleva A, Smith C, Liu F, Li J, Poleshko A, et al.
Dev Biol
. 2020 Jul;
466(1-2):90-98.
PMID: 32712024
Spatial organization of the genome in the nucleus plays a critical role in development and regulation of transcription. A genomic region that resides at the nuclear periphery is part of...
8.
Aghajanian H, Kimura T, Rurik J, Hancock A, Leibowitz M, Li L, et al.
Nature
. 2019 Nov;
576(7785):E2.
PMID: 31723271
An Amendment to this paper has been published and can be accessed via a link at the top of the paper.
9.
Poleshko A, Smith C, Nguyen S, Sivaramakrishnan P, Wong K, Murray J, et al.
Elife
. 2019 Oct;
8.
PMID: 31573510
Cell-type-specific 3D organization of the genome is unrecognizable during mitosis. It remains unclear how essential positional information is transmitted through cell division such that a daughter cell recapitulates the spatial...
10.
Aghajanian H, Kimura T, Rurik J, Hancock A, Leibowitz M, Li L, et al.
Nature
. 2019 Sep;
573(7774):430-433.
PMID: 31511695
Fibrosis is observed in nearly every form of myocardial disease. Upon injury, cardiac fibroblasts in the heart begin to remodel the myocardium by depositing excess extracellular matrix, resulting in increased...