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Cheol Won Park

Explore the profile of Cheol Won Park including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 37
Followers 0
Related Specialties
Biochemistry
Molecular Biology
Endocrinology
Top 10 Co-Authors
Hyun Chul Lee
Chul Woo Ahn
Bong Soo Cha
Koo Lee
Yongho Lee
Won-Hyuk Jung
Young Mi Park
Kyung-Sup Kim
O Hwan Kwon
Sun Hwa Lee
Published In
Bioorg Med Chem Lett
J Gene Med
J Med Chem
Diabetes Res Clin Pract
Biochem Biophys Res Commun
Affiliations
Soon will be listed here.
Recent Articles
1.
Relationship of serum high sensitivity C-reactive protein to metabolic syndrome and microvascular complications in type 2 diabetes
Kang E, Kim H, Ahn C, Park C, Cha B, Lim S, et al.
Diabetes Res Clin Pract . 2005 Jul; 69(2):151-9. PMID: 16005364
The high sensitivity C-reactive protein (hsCRP) is known to be a sensitive predictor of coronary heart disease and type 2 diabetes. This study evaluated the association between the serum hsCRP...
2.
Safety and efficacy of adeno-associated viral vector-mediated insulin gene transfer via portal vein to the livers of streptozotocin-induced diabetic Sprague-Dawley rats
Park Y, Woo S, Lee G, Ko J, Lee Y, Zhao Z, et al.
J Gene Med . 2005 Jan; 7(5):621-9. PMID: 15651056
Background: Previous studies demonstrating the efficacy of insulin gene therapy have mostly involved use of adenoviral vectors or naked DNA to deliver the insulin gene. However, this procedure may not...
3.
Targeting of therapeutic gene expression to the liver by using liver-type pyruvate kinase proximal promoter and the SV40 viral enhancer active in multiple cell types
Park C, Park Y, Lee G, Lee Y, Woo S, Cha J, et al.
Biochem Biophys Res Commun . 2004 Jan; 314(1):131-7. PMID: 14715256
To achieve the liver-directed expression in sufficient amounts of therapeutic genes for successful and safe gene therapy, natural liver-specific promoters can be used to direct the expression of therapeutic genes...
4.
Efficacious and orally bioavailable thrombin inhibitors based on a 2,5-thienylamidine at the P1 position: discovery of N-carboxymethyl-d-diphenylalanyl-l-prolyl[(5-amidino-2-thienyl)methyl]amide
Lee K, Park C, Jung W, Park H, Lee S, Chung K, et al.
J Med Chem . 2003 Aug; 46(17):3612-22. PMID: 12904065
Thrombin, a crucial enzyme in the blood coagulation, has been a target for antithrombotic therapy. Orally active thrombin inhibitors would provide effective and safe prophylaxis for venous and arterial thrombosis....
5.
Noncovalent tripeptidic thrombin inhibitors incorporating amidrazone, amine and amidine functions at P1
Lee K, Jung W, Park C, Park H, Lee S, Kwon O
Bioorg Med Chem Lett . 2002 Mar; 12(7):1017-22. PMID: 11909707
A series of noncovalent tripeptidic thrombin inhibitors incorporating amidrazone, amine and amidine functions at P1 was investigated. While the amidrazone and the amine series displayed limited oral absorption, the amidine...