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Chennagiri R Pandit

Explore the profile of Chennagiri R Pandit including associated specialties, affiliations and a list of published articles. Areas
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Citations 73
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Recent Articles
1.
Letavic M, Aluisio L, Apodaca R, Bajpai M, Barbier A, Bonneville A, et al.
ACS Med Chem Lett . 2015 Apr; 6(4):450-4. PMID: 25893048
The preclinical characterization of novel phenyl(piperazin-1-yl)methanones that are histamine H3 receptor antagonists is described. The compounds described are high affinity histamine H3 antagonists. Optimization of the physical properties of these...
2.
Mapes C, Mani N, Deng X, Pandit C, McClure K, Pippel M, et al.
J Org Chem . 2010 Oct; 75(22):7950-3. PMID: 20977279
We describe a practical and scalable route to compound (Z)-1, a selective CCK1 receptor antagonist. Notable features of this concise route are (1) a regioselective construction of the pyrazole core...
3.
Arienti K, Brunmark A, Axe F, McClure K, Lee A, Blevitt J, et al.
J Med Chem . 2005 Mar; 48(6):1873-85. PMID: 15771432
The discovery of a series of novel, potent, and highly selective inhibitors of the DNA damage control kinase chk2 is disclosed. Here we report the first SAR study around inhibitors...
4.
Wrobleski S, Chen P, Hynes Jr J, Lin S, Norris D, Pandit C, et al.
J Med Chem . 2003 May; 46(11):2110-6. PMID: 12747783
A series of unique indazoles and pyridoindolones have been rationally designed and synthesized as novel classes of cannabinoid ligands based on a proposed bioactive amide conformation. This has led to...