Chengyuan Mao
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Explore the profile of Chengyuan Mao including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
432
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Recent Articles
1.
E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A
Hao X, Hu Z, Li M, Zhang S, Tang M, Hao C, et al.
EMBO J
. 2025 Jan;
44(4):1249-1273.
PMID: 39806097
The carboxyl terminus of Hsc70-interacting protein (CHIP) is pivotal for managing misfolded and aggregated proteins via chaperone networks and degradation pathways. In a preclinical rodent model of CHIP-related ataxia, we...
2.
Su Y, Zheng H, Cui X, Zhang S, Zhang S, Hu Z, et al.
Ageing Res Rev
. 2024 Oct;
102:102553.
PMID: 39454761
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, with an unknown etiology and no specific treatment. Emerging single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) technologies have become instrumental in...
3.
Cui X, Li X, Zheng H, Su Y, Zhang S, Li M, et al.
NPJ Parkinsons Dis
. 2024 Oct;
10(1):189.
PMID: 39428415
Parkinson's disease (PD) is a neurodegenerative disorder marked by the loss of dopaminergic neurons in the substantia nigra. Despite progress, the pathogenesis remains unclear. Human midbrain organoids (hMLOs) have emerged...
4.
Mao C, Cui X, Zhang S
Int J Neurosci
. 2024 Sep;
:1-8.
PMID: 39320971
Background: Autoimmune encephalitis (AE) is a group of autoimmune diseases targeting the central nervous system, characterized by severe clinical symptoms and substantial consumption of medical resources. Neuroinflammation plays a crucial...
5.
Li M, Hao X, Hu Z, Tian J, Shi J, Ma D, et al.
Sci Rep
. 2024 Sep;
14(1):20944.
PMID: 39251797
Alzheimer's disease (AD) is the most common cause of dementia, characterized by memory loss, cognitive decline, personality changes, and various neurological symptoms. The role of blood-brain barrier (BBB) injury, extracellular...
6.
Shi C, Ma D, Li M, Wang Z, Hao C, Liang Y, et al.
NPJ Parkinsons Dis
. 2024 Sep;
10(1):166.
PMID: 39242620
There is considerable uncertainty regarding the associations between various risk factors and Parkinson's Disease (PD). This study systematically screened and validated a wide range of potential PD risk factors from...
7.
Wang Z, Li M, Ma D, Guo M, Hao X, Hu Z, et al.
Gut
. 2024 Jun;
74(1):e10.
PMID: 38889961
No abstract available.
8.
Hu Z, Yang J, Zhang S, Li M, Zuo C, Mao C, et al.
Neural Regen Res
. 2024 May;
20(1):253-264.
PMID: 38767490
JOURNAL/nrgr/04.03/01300535-202501000-00033/figure1/v/2024-05-14T021156Z/r/image-tiff The E3 ubiquitin ligase, carboxyl terminus of heat shock protein 70 (Hsp70) interacting protein (CHIP), also functions as a co-chaperone and plays a crucial role in the protein quality...
9.
Yuan Y, Wang Y, Liu M, Luo H, Liu X, Li L, et al.
Front Neurol
. 2024 May;
15:1404492.
PMID: 38751879
Background: Cutaneous phosphorylated alpha-synuclein (p-α-syn) deposition is an important biomarker of idiopathic Parkinson's disease (iPD). Recent studies have reported synucleinopathies in patients with common genetic forms of PD. Objective: This...
10.
Hu Z, Zuo C, Mao C, Shi C, Xu Y
Front Neurosci
. 2024 Jan;
17:1269354.
PMID: 38188028
Introduction: The peripheral immune system changes in amyotrophic lateral sclerosis (ALS), but the causal relationship between the two is still controversial. Methods: In this study, we aimed to estimate the...